PPP3R2 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PPP3R2	TFCP2
Description		protein phosphatase 3 regulatory subunit B, beta	transcription factor CP2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Calcineurin Complex Protein Serine/threonine Phosphatase Complex Sperm Flagellum Sperm Midpiece Sperm Mitochondrial Sheath	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Phosphatase Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Penetration Of Zona Pellucida Positive Regulation Of Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Calcium Ion Import Across Plasma Membrane Negative Regulation Of Calcium Ion Import Across Plasma Membrane	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Cyclosporine Voclosporin
Diseases
GWAS
Interacting Genes		18 interacting genes: APC AURKA BUB1 CCND1 CD14 DLC1 DYNLL1 FBXW7 KRT34 MLH3 MSH2 PDGFRL PTPN12 PTPRJ RAB32 SMAD4 TBC1D10C TFCP2	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		5535	7024
HPRD ID		10164	01790
Ensembl ID		ENSG00000188386	ENSG00000135457
Uniprot IDs		Q96LZ3	Q12800
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Centromeric DNA Binding Kinetochore Negative Regulation Of Mitotic Cell Cycle Gamma-catenin Binding Mismatched DNA Binding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway DNA Damage Response Ruffle Membrane ATP-dependent DNA Damage Sensor Activity Negative Regulation Of Cell Cycle Process Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Signal Transduction Regulation Of Programmed Cell Death Negative Regulation Of Cytoskeleton Organization Regulation Of Apoptotic Process Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Supramolecular Fiber Organization Protein-containing Complex Binding Negative Regulation Of Phosphate Metabolic Process Response To Stress Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Cell Communication Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle Negative Regulation Of Signaling Negative Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Liver Regeneration Response To UV Response To X-ray Cell Cycle Phase Transition Regeneration Organelle Organization Chromosome Organization Mismatch Repair Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
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