TCP11L1 and HMG20A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCP11L1	HMG20A
Description		t-complex 11 like 1	high mobility group 20A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Microtubule	Nucleus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Anger ( 24489884) Platelet distribution width ( 32888494)	Fasting glucose ( 34059833) Femur bone mineral density x serum urate levels interaction ( 34046847) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 21874001 22693455 22885922 24509480 28869590 30054458 30297969 30718926 32499647)
Interacting Genes		24 interacting genes: APP CNOT7 DDIT4L ERCC6L2 HMG20A IKBKG IPO4 LHX2 MAGEA12 MEOX1 NEDD4 OGT PAX6 PLEKHS1 PRXL2B PSMD4 REL SDCBP2 SNW1 TBX6 TRIM21 TSNAX VPS52 WWTR1	59 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNB DYRK1A FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM11 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1
Entrez ID		55346	10363
HPRD ID		07750	16116
Ensembl ID		ENSG00000176148	ENSG00000140382
Uniprot IDs		B3KQZ4 Q9NUJ3	B4DMG1 Q9NP66
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telencephalon Regionalization Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Canonical NF-kappaB Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process HMG Box Domain Binding Regulation Of Neuron Differentiation Transcription Corepressor Activity Positive Regulation Of Metabolic Process Negative Regulation Of Post-translational Protein Modification DNA Binding Sequence-specific DNA Binding Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Chromatin Protein-containing Complex Regulation Of Primary Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catabolic Process Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Formation Of Structure Involved In A Symbiotic Process Forebrain-midbrain Boundary Formation Signal Transduction Involved In Regulation Of Gene Expression	Protein Binding
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