TCP11L1 and TSNAX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCP11L1	TSNAX
Description		t-complex 11 like 1	translin associated factor X
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Endoribonuclease Complex
	Molecular Function	Protein Binding	DNA Binding Single-stranded DNA Binding RNA Binding RNA Endonuclease Activity Protein Binding A2A Adenosine Receptor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Signal Transduction	Spermatogenesis Cell Differentiation SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Pathways			Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Anger ( 24489884) Platelet distribution width ( 32888494)	Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APP CNOT7 DDIT4L ERCC6L2 HMG20A IKBKG IPO4 LHX2 MAGEA12 MEOX1 NEDD4 OGT PAX6 PLEKHS1 PRXL2B PSMD4 REL SDCBP2 SNW1 TBX6 TRIM21 TSNAX VPS52 WWTR1	41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEBPA CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KRT31 LDB2 LDOC1 LZTS2 MECOM MRFAP1L1 MTCL2 NSMCE2 NTAQ1 PBXIP1 PRPF18 RALYL RFC5 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28
Entrez ID		55346	7257
HPRD ID		07750	04270
Ensembl ID		ENSG00000176148	ENSG00000116918
Uniprot IDs		B3KQZ4 Q9NUJ3	Q99598
PDB IDs			3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telencephalon Regionalization Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Canonical NF-kappaB Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process HMG Box Domain Binding Regulation Of Neuron Differentiation Transcription Corepressor Activity Positive Regulation Of Metabolic Process Negative Regulation Of Post-translational Protein Modification DNA Binding Sequence-specific DNA Binding Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Chromatin Protein-containing Complex Regulation Of Primary Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catabolic Process Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Formation Of Structure Involved In A Symbiotic Process Forebrain-midbrain Boundary Formation Signal Transduction Involved In Regulation Of Gene Expression
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