TCP11L1 and PLEKHS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCP11L1	PLEKHS1
Description		t-complex 11 like 1	pleckstrin homology domain containing S1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Microtubule
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Anger ( 24489884) Platelet distribution width ( 32888494)
Interacting Genes		24 interacting genes: APP CNOT7 DDIT4L ERCC6L2 HMG20A IKBKG IPO4 LHX2 MAGEA12 MEOX1 NEDD4 OGT PAX6 PLEKHS1 PRXL2B PSMD4 REL SDCBP2 SNW1 TBX6 TRIM21 TSNAX VPS52 WWTR1	2 interacting genes: PDCD10 TCP11L1
Entrez ID		55346	79949
HPRD ID		07750	12591
Ensembl ID		ENSG00000176148	ENSG00000148735
Uniprot IDs		B3KQZ4 Q9NUJ3	A0A384P5Z2 Q5SXH7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telencephalon Regionalization Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Canonical NF-kappaB Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process HMG Box Domain Binding Regulation Of Neuron Differentiation Transcription Corepressor Activity Positive Regulation Of Metabolic Process Negative Regulation Of Post-translational Protein Modification DNA Binding Sequence-specific DNA Binding Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Chromatin Protein-containing Complex Regulation Of Primary Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catabolic Process Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Formation Of Structure Involved In A Symbiotic Process Forebrain-midbrain Boundary Formation Signal Transduction Involved In Regulation Of Gene Expression	Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Golgi Localization Wound Healing, Spreading Of Cells FAR/SIN/STRIPAK Complex Endothelium Development Contractile Actin Filament Bundle Assembly Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Establishment Of Golgi Localization Stress Fiber Assembly Golgi Reassembly Positive Regulation Of Peptidyl-serine Phosphorylation Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Positive Regulation Of MAP Kinase Activity Regulation Of Stress-activated MAPK Cascade Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Notch Signaling Pathway
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