GIMAP5 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GIMAP5	STX4
Gene Name		GTPase, IMAP family member 5	syntaxin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Lysosome Integral Component Of Membrane	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	GTP Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process		Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP EDA GRAMD3 LDLRAD1 LSMEM2 STX4	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		55340	6810
HPRD ID		16280	01722
Ensembl ID		ENSG00000196329	ENSG00000103496
Uniprot IDs		Q96F15	A8MXY0 B7Z425 Q12846
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Collateral Sprouting In Absence Of Injury Trachea Gland Development Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Protein Transport Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Salivary Gland Cavitation Positive Regulation Of Protein Localization To Cell Surface Blood Coagulation Response To Oxidative Stress Hemostasis Positive Regulation Of Immunoglobulin Secretion Neuron Remodeling SNARE Complex Assembly Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Regulation Of Signal Transduction Regulation Of Body Fluid Levels Regulation Of Immunoglobulin Secretion Wound Healing Regulation Of Protein Transport Secretion Hair Follicle Placode Formation Cellular Copper Ion Homeostasis Regulation Of Signaling Regulation Of Establishment Of Protein Localization Cell Activation Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Response To Wounding Positive Regulation Of NF-kappaB Import Into Nucleus Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Transport Response To Hydroperoxide Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ectoderm Development Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Trachea Development	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		adipocyte adipocytes adipogenesis adiponectin adipose autonomous biogenesis ca calcineurin causative cisd2 cytosolic defects epididymal ewat functioning homeostasis knockout ko maintenance mitochondria modulate mystery played resolve seem wat wfs wolfram	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		adipocyte adipocytes adipogenesis adiponectin adipose autonomous biogenesis ca calcineurin causative cisd2 cytosolic defects epididymal ewat functioning homeostasis knockout ko maintenance mitochondria modulate mystery played resolve seem wat wfs wolfram	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Intersection) ?