SLC39A9 and CRB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC39A9	CRB3
Description		solute carrier family 39 member 9	crumbs cell polarity complex component 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Mitochondrial Membrane Perinuclear Region Of Cytoplasm	Plasma Membrane Bicellular Tight Junction Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Subapical Complex Apical Junction Complex Apical Part Of Cell Extracellular Exosome Anchoring Junction
	Molecular Function	G Protein-coupled Receptor Activity Zinc Ion Transmembrane Transporter Activity Androgen Binding Protein Binding Zinc Efflux Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Transmembrane Transport Bicellular Tight Junction Assembly Zinc Ion Transmembrane Transport Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Cellular Response To Testosterone Stimulus	Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions SARS-CoV-2 targets PDZ proteins in cell-cell junction
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		40 interacting genes: ANKRD46 APH1A AQP6 BNIP2 CBARP CD79A CERS3 CPLX4 CRB3 CREB3L1 CREB3L3 CYB5B ELOVL5 EVI2B FCER1G FFAR2 GJA8 GPR101 HERPUD2 HTR2C LNPEP MANBAL MGST3 NEU1 RTP2 SERINC2 SLC10A6 SLC16A2 SLC39A2 SLC61A1 SLC66A1 SLC71A2 SLC7A1 SSMEM1 TM4SF18 TMEM140 TMEM237 TMEM86B TRHR VMP1	28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6
Entrez ID		55334	92359
HPRD ID		15387	16749
Ensembl ID		ENSG00000029364	ENSG00000130545
Uniprot IDs		B4DDK0 C4N9M8 M0QX28 Q9NUM3	Q9BUF7
PDB IDs			5I7Z
Enriched GO Terms of Interacting Partners?		Membrane Lysine Transport Plasma Membrane Positive Regulation Of Acute Inflammatory Response L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport L-lysine Transmembrane Transport Regulation Of Acute Inflammatory Response Basic Amino Acid Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Aromatic Amino Acid Transport L-arginine Transmembrane Transport Azole Transmembrane Transport Endoplasmic Reticulum Membrane Basic Amino Acid Transmembrane Transport Protein Binding Transmembrane Transport Amino Acid Transmembrane Transport Basic Amino Acid Transport Response To Unfolded Protein Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling	Endoplasmic Reticulum Membrane SNAP Receptor Activity Membrane SNARE Complex Heme Oxidation Heme Oxygenase (decyclizing) Activity Vesicle Fusion Organelle Membrane Fusion Golgi Apparatus Endomembrane System Organelle Fusion Vesicle Fusion With Golgi Apparatus Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Endoplasmic Reticulum Establishment Or Maintenance Of Apical/basal Cell Polarity Heme Catabolic Process Membrane Fusion Porphyrin-containing Compound Catabolic Process Myelin Assembly Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Organization Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Amyloid Fibril Formation Apical Junction Complex Bicellular Tight Junction Protein Binding Autophagy Heme Metabolic Process Vesicle Organization Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Protein Localization To Myelin Sheath Abaxonal Region Tight Junction Porphyrin-containing Compound Metabolic Process Macroautophagy Establishment Or Maintenance Of Cell Polarity
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