IMP3 and PPP1R12C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IMP3	PPP1R12C
Description		IMP U3 small nucleolar ribonucleoprotein 3	protein phosphatase 1 regulatory subunit 12C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Preribosome Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex	Stress Fiber Cytoplasm Cytoskeleton
	Molecular Function	RNA Binding Protein Binding RRNA Binding SnoRNA Binding	Enzyme Inhibitor Activity Protein Binding Myosin Phosphatase Regulator Activity Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	RRNA Processing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis	Signal Transduction Neuron Projection Morphogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX	27 interacting genes: AIRIM ATP6V1H ATXN7 BHLHA9 CACNA1A CCDC185 CDC42BPA EHHADH EXOC3 FMR1 FXR1 FXR2 IL16 IMP3 MPRIP MYL2 NOD2 NXF1 PAFAH1B2 PPP1CB RBM17 SMAD3 SMARCA2 SPECC1L THOC1 TSFM USHBP1
Entrez ID		55272	54776
HPRD ID		12664	11452
Ensembl ID		ENSG00000177971	ENSG00000125503
Uniprot IDs		Q9NV31	Q9BZL4
PDB IDs		2CQJ 7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?			Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Long-term Neuronal Synaptic Plasticity MRNA Transport Translation Regulator Activity RNA Transport Regulation Of Long-term Neuronal Synaptic Plasticity Cytoplasmic Stress Granule Nucleobase-containing Compound Transport RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Regulation Of Neuronal Synaptic Plasticity MRNA Export From Nucleus Positive Regulation Of MiRNA-mediated Gene Silencing Transcription Export Complex Cytosol Protein Heterodimerization Activity Positive Regulation Of Interleukin-1 Production RNA Export From Nucleus Cytoplasmic Ribonucleoprotein Granule Nucleolus MRNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Interleukin-1 Production Positive Regulation Of Positive Chemotaxis Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Nuclear Export MRNA 3'-UTR Binding Negative Regulation Of Microtubule Depolymerization Protein Binding Positive Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Muscle Cell Fate Specification Myosin-light-chain-phosphatase Activity Regulation Of Microtubule Depolymerization Neural Crest Cell Delamination Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Positive Regulation Of Catabolic Process Cytoplasm Neuron Projection Nucleic Acid Binding RNA Binding Positive Regulation Of Translation
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