IMP3 and KLC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		IMP3	KLC3
Description		IMP U3 small nucleolar ribonucleoprotein 3	kinesin light chain 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Preribosome Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	RNA Binding Protein Binding RRNA Binding SnoRNA Binding	Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	RRNA Processing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis	Microtubule-based Movement Spermatogenesis Spermatid Development Axo-dendritic Transport Cell Differentiation Sperm Mitochondrial Sheath Assembly
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX	41 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		55272	147700
HPRD ID		12664	03212
Ensembl ID		ENSG00000177971	ENSG00000104892
Uniprot IDs		Q9NV31	Q6P597
PDB IDs		2CQJ 7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?			Ciliary Rootlet Organelle Localization Establishment Of Organelle Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Anterograde Dendritic Transport Protein Transport Along Microtubule Anterograde Axonal Transport Establishment Of Vesicle Localization Identical Protein Binding Dendritic Transport Vesicle Localization Plus-end-directed Microtubule Motor Activity Axon Cytoplasm Retrograde Axonal Transport Axonal Transport Dendrite Cytoplasm Axo-dendritic Transport Postsynaptic Cytosol Protein Binding Retrograde Neuronal Dense Core Vesicle Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Transport Along Microtubule Kinesin Complex Microtubule-based Transport Establishment Of Localization In Cell Dense Core Granule Cytoskeletal Transport Receptor Localization To Synapse Presynapse Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cytosolic Transport Vesicle Fusion To Plasma Membrane Vesicle Cytoskeletal Trafficking Microtubule Binding Microtubule Motor Activity Intracellular Transport Protein Localization To Synapse Microtubule-based Process Synaptic Vesicle Membrane Organization Intracellular Protein Localization Insulin-like Growth Factor Receptor Binding Establishment Of Protein Localization Intermediate Filament Organization Secretory Granule Localization Protein Localization To Cell Junction Intermediate Filament Cytoskeleton Organization
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