MRGBP and ACTL6A

Number of citations of the paper that reports this interaction (PMID 12963728)
65

Data Source:
HPRD (in vitro)

		MRGBP	ACTL6A
Gene Name		MRG/MORF4L binding protein	actin-like 6A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm H4/H2A Histone Acetyltransferase Complex	Nuclear Chromatin Nucleus Nucleoplasm Plasma Membrane SWI/SNF Complex Ino80 Complex NuA4 Histone Acetyltransferase Complex Protein Complex NpBAF Complex
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Growth	Neural Retina Development DNA Repair DNA Recombination Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Nervous System Development Regulation Of Growth ATP-dependent Chromatin Remodeling Histone H4 Acetylation Histone H2A Acetylation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Chromatin modifying enzymes Chromatin organization HATs acetylate histones RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACTB ACTL6A BRD8 DMAP1 ING1 KRTAP10-7 MEAF6 MORF4L1 MORF4L2 MSL1 NOTCH2NL RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	13 interactors: ARHGDIA CDK2 CDK9 EWSR1 FLII MRGBP MYC POLR2A RELA RUVBL1 SMARCA2 SMARCA4 TRRAP
Entrez ID		55257	86
HPRD ID		16646	05389
Ensembl ID		ENSG00000101189	ENSG00000136518
Uniprot IDs		A8C4L5 Q9NV56	O96019
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H2A Acetylation Histone H4 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Chromatin Modification Chromatin Organization Peptidyl-lysine Modification Chromosome Organization Histone Modification Regulation Of Growth Organelle Organization Peptidyl-amino Acid Modification DNA Repair Transcription, DNA-templated Chromatin Remodeling RNA Biosynthetic Process Cellular Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling DNA Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Cellular Protein Modification Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Response To Stress Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process DNA Recombination Cellular Response To Stimulus Protein Metabolic Process Mitotic Cell Cycle Process Nucleobase-containing Compound Metabolic Process Response To Stimulus Mitotic Cell Cycle Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Ephrin Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Chromatin Organization Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Aortic Smooth Muscle Cell Differentiation Regulation Of Metabolic Process Chromosome Organization Positive Regulation Of Viral Transcription Chromatin Remodeling Negative Regulation Of Cell Cycle Cellular Response To DNA Damage Stimulus Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Positive Regulation Of Gene Expression Regulation Of Viral Transcription Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Process DNA Metabolic Process DNA Repair Histone H2A Acetylation Histone Acetylation Vascular Smooth Muscle Cell Differentiation Internal Peptidyl-lysine Acetylation Positive Regulation Of Transcription, DNA-templated Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Histone Modification Protein Acetylation Organelle Organization Regulation Of Viral Process Regulation Of Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
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