MRGBP and MORF4L2

Number of citations of the paper that reports this interaction (PubMedID 12963728)
0

Data Source:
HPRD (in vitro)

		MRGBP	MORF4L2
Description		MRG domain binding protein	mortality factor 4 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex H4/H2A Histone Acetyltransferase Complex	Nucleosome Nucleus Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS			Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494)
Interacting Genes		25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	54 interacting genes: AMOTL2 ARID3A BCL11A BEND7 BEX5 CAMK2B CDR2 CEP55 DDIT4L DISC1 DSCAM EVI5 FAM9B FBXO16 GOLGA2 GPBP1 GRAMD2B HDAC1 HMBOX1 HOMEZ HUNK IKZF1 KCTD1 KLHL3 L3MBTL3 LUZP4 LZTS2 MEOX2 MRFAP1 MRGBP MRPL12 NAB2 PHC2 PIBF1 PICK1 PNMA2 POU6F2 RB1 REL SIN3A SYN3 THAP1 TLE1 TLE5 TNIP1 TNNT2 TRIM41 TSN ZBTB10 ZBTB14 ZBTB26 ZBTB43 ZBTB7B ZNF48
Entrez ID		55257	9643
HPRD ID		16646	02326
Ensembl ID		ENSG00000101189	ENSG00000123562
Uniprot IDs		Q9NV56	Q15014
PDB IDs		2N1D
Enriched GO Terms of Interacting Partners?		NuA4 Histone Acetyltransferase Complex Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Nucleosome Regulation Of DNA Recombination Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of DNA Repair Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Chromatin Organization Regulation Of DNA Metabolic Process Swr1 Complex Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Chromatin Remodeling Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Nuclear Matrix Positive Regulation Of Stem Cell Population Maintenance Intermediate Filament Regulation Of Stem Cell Population Maintenance Brahma Complex NpBAF Complex GBAF Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage RSC-type Complex Ino80 Complex Negative Regulation Of GTPase Activity Regulation Of DNA Strand Elongation Syntaxin-1 Binding Structural Constituent Of Cytoskeleton Sin3-type Complex Regulation Of Synaptic Vesicle Endocytosis Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of DNA Replication Regulation Of RNA Biosynthetic Process DNA Repair Regulation Of Nucleotide-excision Repair Regulation Of Macromolecule Biosynthetic Process	Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Corepressor Activity Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Nucleoplasm Regulation Of Axon Extension RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Importin-alpha Family Protein Binding Positive Regulation Of Cell Development Positive Regulation Of Neurogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Neurogenesis
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