ELP1 and SDHAF2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ELP1	SDHAF2
Description		elongator acetyltransferase complex subunit 1	succinate dehydrogenase complex assembly factor 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Elongator Holoenzyme Complex	Nucleolus Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	TRNA Binding Protein Binding	Protein Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Translation TRNA Processing	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Protein Dephosphorylation Negative Regulation Of Epithelial To Mesenchymal Transition Protein-FAD Linkage Mitochondrial Respiratory Chain Complex II Assembly Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		HATs acetylate histones	Maturation of TCA enzymes and regulation of TCA cycle
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		27 interacting genes: BAG6 BARD1 CCT5 CDKN2B CHUK CSTF2 ELP2 ELP3 ELP6 HTT IKBKB IRF4 MAN2A2 MAP3K14 MAP3K7 MAPK8 MRPL42 NDUFB9 NFKBIA NIPSNAP3A PBX2 PLP2 SDHAF2 SNAPIN TAC3 TTR TXNDC9	6 interacting genes: CCDC90B CYP4F2 EEF1A1 ELP1 IMMT SEC22A
Entrez ID		8518	54949
HPRD ID		04763	07915
Ensembl ID		ENSG00000070061	ENSG00000167985
Uniprot IDs		A0A6Q8PGW3 A0A6Q8PHA0 B3KNB2 B4E3I9 F5H2T0 O95163 Q8N516	Q9NX18
PDB IDs		5CQR 8PTX 8PTY 8PTZ 8PU0	6VAX 8DYD
Enriched GO Terms of Interacting Partners?		Non-canonical NF-kappaB Signal Transduction Elongator Holoenzyme Complex TRNA Wobble Uridine Modification Immune Response-regulating Signaling Pathway Canonical NF-kappaB Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway IkappaB Kinase Activity Fc-epsilon Receptor Signaling Pathway Stress-activated MAPK Cascade Innate Immune Response-activating Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Interleukin-1-mediated Signaling Pathway Cellular Response To Tumor Necrosis Factor Activation Of Innate Immune Response Immune Response-activating Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Response To Tumor Necrosis Factor Immune Response-activating Cell Surface Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Activation Of Immune Response Cell Surface Toll-like Receptor Signaling Pathway IkappaB Kinase Complex Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Innate Immune Response Regulation Of Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Fc Receptor Signaling Pathway Positive Regulation Of Innate Immune Response Tumor Necrosis Factor-mediated Signaling Pathway CD40 Receptor Complex Transferrin Receptor Binding TRIF-dependent Toll-like Receptor Signaling Pathway Cytosol Scaffold Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MAP Kinase Activity Regulation Of Cytokine Production Involved In Inflammatory Response TRNA Modification Protein Serine/threonine Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Immune Response Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway	TRNA Binding Eukaryotic Translation Elongation Factor 1 Complex TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Elongator Holoenzyme Complex Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Phylloquinone Catabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Leukotriene B4 Catabolic Process Vitamin K Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Vitamin E Metabolic Process Alkane 1-monooxygenase Activity Menaquinone Metabolic Process 20-aldehyde-leukotriene B4 20-monooxygenase Activity Fatty Acid Omega-oxidation Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Menaquinone Catabolic Process Mitochondrial Crista Junction MICOS Complex Regulation Of Chaperone-mediated Autophagy Long-chain Fatty Acid Catabolic Process Negative Regulation Of Fatty Acid Transport Host-mediated Activation Of Viral Genome Replication Arachidonate Epoxygenase Activity Omega-hydroxylase P450 Pathway SAM Complex MIB Complex Host-mediated Perturbation Of Viral Genome Replication Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Cristae Formation Kinase Activator Activity Cytoplasmic Side Of Lysosomal Membrane Vitamin K Metabolic Process TRNA Wobble Uridine Modification Epoxygenase P450 Pathway Mitochondrial Envelope Positive Regulation Of Icosanoid Secretion Ketone Catabolic Process Translation Elongation Factor Activity Renal Water Homeostasis Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Fatty Acid Transport Mitochondrial Calcium Ion Homeostasis Inorganic Ion Homeostasis Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Vitamin Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?