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IKBKAP and NDUFB9
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
IKBKAP
NDUFB9
Gene Name
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleolus
Cytoplasm
Transcription Elongation Factor Complex
Elongator Holoenzyme Complex
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex I
Extracellular Vesicular Exosome
Molecular Function
RNA Polymerase II Core Binding
Signal Transducer Activity
Protein Binding
Phosphorylase Kinase Regulator Activity
NADH Dehydrogenase (ubiquinone) Activity
Biological Process
Chromatin Organization
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Protein Complex Assembly
Protein Phosphorylation
Immune Response
Signal Transduction
Positive Regulation Of Cell Migration
Regulation Of Protein Kinase Activity
Mitochondrial Electron Transport, NADH To Ubiquinone
Sensory Perception Of Sound
Respiratory Electron Transport Chain
Cellular Metabolic Process
Small Molecule Metabolic Process
Pathways
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Respiratory electron transport
The citric acid (TCA) cycle and respiratory electron transport
Drugs
NADH
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
BAG6
BARD1
CCT5
CDKN2B
CHUK
CSTF2
ELP2
ELP3
HTT
IKBKB
IRF4
MAN2A2
MAP3K14
MAP3K7
MAPK8
MRPL42
NDUFB9
NFKBIA
NIPSNAP3A
PBX2
PLP2
SDHAF2
SNAPIN
TAC3
TTR
TXNDC9
10 interactors:
FEZ1
GDF9
HAP1
IKBKAP
IMMT
MAGEA11
MEF2A
RBBP6
SH3GL3
XRN1
Entrez ID
8518
4715
HPRD ID
04763
03264
Ensembl ID
ENSG00000070061
ENSG00000147684
Uniprot IDs
O95163
Q8N516
E9PF49
Q9Y6M9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
I-kappaB Kinase/NF-kappaB Signaling
I-kappaB Phosphorylation
Response To External Stimulus
Positive Regulation Of Innate Immune Response
Fc-epsilon Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Innate Immune Response
T Cell Receptor Signaling Pathway
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Fc Receptor Signaling Pathway
Internal Protein Amino Acid Acetylation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Acetylation
Antigen Receptor-mediated Signaling Pathway
Histone H3 Acetylation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cytokine Production
Negative Regulation Of Programmed Cell Death
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Peptidyl-amino Acid Modification
Regulation Of Signal Transduction
Negative Regulation Of Cell Death
Intracellular Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Organic Substance
Neurotrophin TRK Receptor Signaling Pathway
Response To Other Organism
Positive Regulation Of Type I Interferon Production
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Mitochondrion Localization
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Positive Regulation Of Neurogenesis
Organelle Localization
Regulation Of Cell Projection Organization
Regulation Of Dendrite Development
Positive Regulation Of Cell Development
Oocyte Growth
Regulation Of Receptor Activity
Positive Regulation Of Cilium Assembly
ERK5 Cascade
Regulation Of Organelle Transport Along Microtubule
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Regulation Of Secretion
Regulation Of Progesterone Secretion
Primary Heart Field Specification
Sinoatrial Valve Morphogenesis
Regulation Of Synaptic Activity
Cellular Response To Trichostatin A
Regulation Of Neurogenesis
Ventricular Cardiac Myofibril Assembly
Nephron Tubule Epithelial Cell Differentiation
Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Muscle Cell Fate Determination
Positive Regulation Of Cell Proliferation In Bone Marrow
Nuclear MRNA Surveillance
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Macrophage Apoptotic Process
Positive Regulation Of Behavioral Fear Response
Neurotrophin Signaling Pathway
RNA Surveillance
Regulation Of Cell Development
Positive Regulation Of Cell Differentiation
Cellular Macromolecule Catabolic Process
RNA Metabolic Process
Cellular Response To Organic Substance
Hypothalamus Cell Differentiation
Histone MRNA Catabolic Process
Anatomical Structure Development
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Homodimerization Activity
Negative Regulation Of Beta-amyloid Formation
Regulation Of Cellular Component Organization
Positive Regulation Of Myeloid Cell Apoptotic Process
Tagcloud
?
advance
autonomously
autosomal
awaited
believed
compensate
deficiencies
devastating
dysautonomia
faithfully
fd
hallmark
ikap
implicating
myelin
myelination
neurodevelopmental
oli
oligodendrocyte
postmortem
proof
reason
recapitulate
recessive
scarcity
severely
skipping
splice
underscoring
Tagcloud (Difference)
?
advance
autonomously
autosomal
awaited
believed
compensate
deficiencies
devastating
dysautonomia
faithfully
fd
hallmark
ikap
implicating
myelin
myelination
neurodevelopmental
oli
oligodendrocyte
postmortem
proof
reason
recapitulate
recessive
scarcity
severely
skipping
splice
underscoring
Tagcloud (Intersection)
?