Wiki-Pi
About
Search
People
Updates
Search
PPP1R8 and WDR77
Number of citations of the paper that reports this interaction (PubMedID
22365833
)
0
Data Source:
BioGRID
(two hybrid)
PPP1R8
WDR77
Description
protein phosphatase 1 regulatory subunit 8
WD repeat domain 77
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Nuclear Speck
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cul4B-RING E3 Ubiquitin Ligase Complex
Methylosome
Transferase Complex
Molecular Function
DNA Binding
RNA Binding
MRNA Binding
Nuclease Activity
Endonuclease Activity
RNA Endonuclease Activity
Protein Phosphatase Inhibitor Activity
Protein Serine/threonine Phosphatase Inhibitor Activity
Protein Binding
Ribonuclease E Activity
Hydrolase Activity
Protein Phosphatase Regulator Activity
Molecular Function Inhibitor Activity
Transcription Coactivator Activity
Protein Binding
Methyl-CpG Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
MRNA Processing
RNA Catabolic Process
Cell Population Proliferation
RNA Splicing
Protein Polyubiquitination
Spliceosomal SnRNP Assembly
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Oocyte Axis Specification
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of MRNA Splicing, Via Spliceosome
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Epithelial Cell Proliferation Involved In Prostate Gland Development
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways
mRNA Splicing - Major Pathway
snRNP Assembly
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes
28 interacting genes:
APP
APPBP2
CDC5L
CNKSR1
CREBBP
CRMP1
CSNK2A1
CSNK2A2
CTNNBL1
EED
ERG28
FBXO25
GBP2
HDAC2
HMGA1
LRRK2
LYN
MELK
PPIL1
PPP1CA
PPP1CC
PRKACA
RBM48
RTN4IP1
SETDB1
SF3B1
STC2
WDR77
46 interacting genes:
AQR
BAG2
CDK19
CDK8
CLNS1A
CREBBP
CTDP1
EIF4A1
GLI1
GPKOW
H2AC21
HNRNPM
LSM3
NKX3-1
PCBP2
PDCD4
PPIL1
PPP1R8
PQBP1
PRKG1
PRKG2
PRMT5
QKI
RBM5
SAP30BP
SF1
SF3A1
SF3B4
SIRT7
SMAD1
SMYD1
SNRPB
SNRPC
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SUZ12
THOC1
TOE1
UBC
YWHAB
YWHAQ
ZMYND19
ZNF207
Entrez ID
5511
79084
HPRD ID
04028
14387
Ensembl ID
ENSG00000117751
ENSG00000116455
Uniprot IDs
Q12972
Q6ICT4
A0A024R0H7
Q9BQA1
PDB IDs
3V4Y
4GQB
4X60
4X61
4X63
5C9Z
5EMJ
5EMK
5EML
5EMM
5FA5
6CKC
6K1S
6RLL
6RLQ
6UGH
6UXX
6UXY
6V0N
6V0O
6V0P
7BO7
7KIB
7KIC
7KID
7L1G
7M05
7MX7
7MXA
7MXC
7MXG
7MXN
7S0U
7S1P
7S1Q
7S1R
7S1S
7SER
7SES
7U30
7UOH
7UY1
7UYF
7ZUP
7ZUQ
7ZUU
7ZUY
7ZV2
7ZVL
7ZVU
8CSG
8CTB
8CYI
8G1U
8VEO
8VET
8VEU
8VEW
8VEX
8VEY
8X6L
9C10
9DOD
9E3A
9E3B
9EYU
9EYV
9EYW
9EYX
9MGL
9MGM
9MGN
9MGP
9MGQ
9MGR
9N3N
9N3O
9N3P
9N3Q
9N3R
Enriched GO Terms of Interacting Partners
?
Macromolecule Metabolic Process
Nucleoplasm
Postsynapse
Cellular Response To Catecholamine Stimulus
Response To Catecholamine
Protein Modification Process
Protein Kinase CK2 Complex
Intracellular Signal Transduction
Protein Metabolic Process
Spliceosomal Complex
Cellular Response To Stress
Regulation Of Proteolysis
Enzyme Binding
MRNA Metabolic Process
Rhythmic Process
Cellular Response To Dopamine
PTW/PP1 Phosphatase Complex
Chromatin Remodeling
Negative Regulation Of Macromolecule Metabolic Process
Signaling Receptor Activator Activity
Nucleobase-containing Compound Metabolic Process
MRNA Processing
Response To Dopamine
Cellular Response To Heat
Perikaryon
Cellular Response To Manganese Ion
Chromatin Binding
Protein Kinase Activity
DNA Repair
Positive Regulation Of Gliogenesis
Regulation Of Carbohydrate Catabolic Process
Negative Regulation Of Metabolic Process
Nucleic Acid Metabolic Process
Circadian Regulation Of Gene Expression
DNA Damage Response
Positive Regulation Of Programmed Cell Death
Nucleus
Response To Manganese Ion
Prp19 Complex
Protein Serine Kinase Activity
Golgi-associated Vesicle
Chromatin Organization
Regulation Of Apoptotic Process
Regulation Of Protein Catabolic Process
RNA Splicing
MRNA Splicing, Via Spliceosome
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Macroautophagy
ESC/E(Z) Complex
Negative Regulation Of Gene Expression
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Spliceosomal Complex
RNA Splicing
MRNA Processing
MRNA Metabolic Process
Methylosome
RNA Processing
RNA Metabolic Process
Spliceosomal Complex Assembly
PICln-Sm Protein Complex
Catalytic Step 2 Spliceosome
U2-type Prespliceosome Assembly
Spliceosomal SnRNP Assembly
U2 SnRNP
Protein-RNA Complex Assembly
Nucleic Acid Metabolic Process
U2-type Spliceosomal Complex
RNA Binding
7-methylguanosine Cap Hypermethylation
U2-type Catalytic Step 2 Spliceosome
U2-type Precatalytic Spliceosome
Nucleoplasm
U1 SnRNP
Nucleus
U4 SnRNP
U12-type Spliceosomal Complex
Nucleobase-containing Compound Metabolic Process
Small Nuclear Ribonucleoprotein Complex
SMN-Sm Protein Complex
Precatalytic Spliceosome
U5 SnRNP
U4/U6 X U5 Tri-snRNP Complex
Macromolecule Metabolic Process
U7 SnRNP
Ribonucleoprotein Complex
MRNA Binding
Macromolecule Methylation
Methylation
RNA Methylation
Commitment Complex
Protein-containing Complex Assembly
Nucleic Acid Binding
Protein-containing Complex Organization
RNA Modification
CGMP-dependent Protein Kinase Activity
MRNA Cis Splicing, Via Spliceosome
U2-type Prespliceosome
Telomerase Holoenzyme Complex
Histone Pre-mRNA DCP Binding
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?