AGGF1 and TOE1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		AGGF1	TOE1
Description		angiogenic factor with G-patch and FHA domains 1	target of EGR1, exonuclease
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	Nucleic Acid Binding Protein Binding Identical Protein Binding	3'-5'-RNA Exonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Protein Binding Zinc Ion Binding SnRNA Binding Metal Ion Binding
	Biological Process	Angiogenesis Vasculogenesis Positive Regulation Of Endothelial Cell Proliferation Cell Adhesion Cell Differentiation Positive Regulation Of Angiogenesis	RNA Metabolic Process SnRNA 3'-end Processing
Pathways		Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: BLOC1S6 CCDC85B CHERP DHX15 FBXO28 IDH1 MAB21L3 MCRS1 RNF10 SNRPC TNFSF12 TOE1	27 interacting genes: ABCF3 AGGF1 ANXA1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 OGT PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		55109	114034
HPRD ID		07621	18212
Ensembl ID		ENSG00000164252	ENSG00000132773
Uniprot IDs		Q8N302	B4DP23 Q96GM8
PDB IDs			2FC6
Enriched GO Terms of Interacting Partners?			MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Spliceosomal Complex MRNA Processing MRNA Metabolic Process Catalytic Step 2 Spliceosome RNA Metabolic Process Nucleoplasm Nuclear Speck Regulation Of RNA Splicing RNA Processing Nucleic Acid Metabolic Process Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RS Domain Binding Regulation Of MRNA Processing Glutamatergic Synapse Cadherin Binding Involved In Cell-cell Adhesion RNA Binding Transition Metal Ion Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Membraneless Organelle Assembly U2-type Spliceosomal Complex Regulation Of Programmed Cell Death Alpha-2B Adrenergic Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Synaptic Vesicle Priming Oocyte Axis Specification
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