RAI1

Description		retinoic acid induced 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Rhythmic Process
Pathways		Heme signaling Expression of BMAL (ARNTL), CLOCK, and NPAS2
Drugs
Diseases		Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
GWAS		A body shape index ( 34021172) Body mass index ( 28892062) Caffeine consumption from coffee ( 33287642) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Glycated hemoglobin levels ( 34059833) Hip circumference ( 25673412) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte count ( 27863252) Monocyte count ( 32888494) Offspring birth weight ( 31043758) Parkinson's disease ( 21738487) Schizophrenia ( 29483656 28991256 25056061) Type 2 diabetes ( 30054458 30297969) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		5 novel interacting genes: CCDC144A GRAP NCOR1 PEMT ULK2
Interacting Genes		17 interacting genes: CASP2 CDKN1A DDIT3 GADD45A GATA1 GLI1 GSK3B LZTR1 MAML3 MAPK8IP2 PIN1 RPS6KA5 TESC TET2 TOPBP1 TTR ZNF496
Entrez ID		10743
HPRD ID		07406
Ensembl ID		ENSG00000108557
Uniprot IDs		Q7Z5J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intracellular Signal Transduction Signal Transduction In Response To DNA Damage Positive Regulation Of RNA Metabolic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Multicellular Organismal Process Regulation Of Transcription By RNA Polymerase II ER Overload Response RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Signaling Pathway Megakaryocyte Differentiation Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Nucleoplasm Regulation Of RNA Metabolic Process Transcription Cis-regulatory Region Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Multicellular Organismal Process Regulation Of Signal Transduction Positive Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of Developmental Growth Intracellular Signaling Cassette Regeneration Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Response To Stress Response To Ionizing Radiation Regulation Of JNK Cascade Positive Regulation Of Biosynthetic Process Mitotic G2 DNA Damage Checkpoint Signaling Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Developmental Process ER-nucleus Signaling Pathway Negative Regulation Of Catalytic Activity Negative Regulation Of Phosphate Metabolic Process Regulation Of MAPK Cascade Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein
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