TRNAU1AP and PRRC2B

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TRNAU1AP	PRRC2B
Description		tRNA selenocysteine 1 associated protein 1	proline rich coiled-coil 2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	TRNA Binding Nucleic Acid Binding RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Selenocysteine Incorporation Translation	Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: BCAS2 DMRTB1 GTSE1 PRPF39 PRRC2B QKI RBM42 SECISBP2 USP10	41 interacting genes: ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CRK CTBP1 DAPK1 DDX11 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A YTHDF1 YTHDF3
Entrez ID		54952	84726
HPRD ID		18035	13805
Ensembl ID		ENSG00000180098	ENSG00000288701
Uniprot IDs		Q9NX07	Q5JSZ5 Q9BU62
PDB IDs		2DHG 2DIV
Enriched GO Terms of Interacting Partners?		RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Processing Stress Granule Assembly Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Splicing, Via Spliceosome DNA Damage Response, Signal Transduction By P53 Class Mediator Membraneless Organelle Assembly RNA Metabolic Process Translational Elongation RNA Binding Regulation Of MRNA Metabolic Process MRNA Stabilization Internal N(7)-methylguanine-containing RNA Reader Activity Nucleobase-containing Compound Metabolic Process RNA Processing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Stress Granule Assembly Myofibroblast Contraction Negative Regulation Of RNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process Signal Transduction By P53 Class Mediator Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA 3'-UTR Binding Spliceosome-depend Formation Of Circular RNA Pre-mRNA 5'-splice Site Binding Selenocysteine Insertion Sequence Binding Commitment Complex Signal Transduction In Response To DNA Damage Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of RNA Splicing Regulation Of MRNA Stability Germ Cell Development Microglia Differentiation Negative Regulation Of Macrophage Differentiation Spliceosomal Complex MRNA 5'-splice Site Recognition Selenocysteine Incorporation Monoubiquitinated Protein Deubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Organelle Assembly Regulation Of RNA Stability Regulation Of Stress Granule Assembly Intracellular MRNA Localization	RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity
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