PRRC2B and NXF5

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		PRRC2B	NXF5
Description		proline rich coiled-coil 2B	nuclear RNA export factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Nuclear RNA Export Factor Complex
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Cell Differentiation	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus RNA Transport MRNA Transport
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)	Chronotype ( 30696823) Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CRK CTBP1 DAPK1 DDX11 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A YTHDF1 YTHDF3	2 interacting genes: NXF1 PRRC2B
Entrez ID		84726	55998
HPRD ID		13805	02263
Ensembl ID		ENSG00000288701	ENSG00000290798
Uniprot IDs		Q5JSZ5 Q9BU62
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity	Nuclear RNA Export Factor Complex Nuclear Inclusion Body Transcription Export Complex Poly(A)+ MRNA Export From Nucleus
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