TRNAU1AP and SECISBP2

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TRNAU1AP	SECISBP2
Description		tRNA selenocysteine 1 associated protein 1	SECIS binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Mitochondrion Ribonucleoprotein Complex
	Molecular Function	TRNA Binding Nucleic Acid Binding RNA Binding Protein Binding	DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Selenocysteine Insertion Sequence Binding Ribonucleoprotein Complex Binding
	Biological Process	Selenocysteine Incorporation Translation	Selenocysteine Incorporation RNA Catabolic Process Translation Striatum Development Forebrain Neuron Development MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways			Selenocysteine synthesis
Drugs
Diseases
GWAS			Trunk fat mass ( 28552196)
Interacting Genes		9 interacting genes: BCAS2 DMRTB1 GTSE1 PRPF39 PRRC2B QKI RBM42 SECISBP2 USP10	9 interacting genes: APP ATXN7L3 DMRTB1 FAM168A GOLGA2 QKI RNF10 SMAD9 TRNAU1AP
Entrez ID		54952	79048
HPRD ID		18035	07408
Ensembl ID		ENSG00000180098	ENSG00000187742
Uniprot IDs		Q9NX07	A0A1S5UZH3 B4DR97 B4DZC7 Q96T21 Q9H948
PDB IDs		2DHG 2DIV	7ZJW 7ZJX
Enriched GO Terms of Interacting Partners?		RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Processing Stress Granule Assembly Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Splicing, Via Spliceosome DNA Damage Response, Signal Transduction By P53 Class Mediator Membraneless Organelle Assembly RNA Metabolic Process Translational Elongation RNA Binding Regulation Of MRNA Metabolic Process MRNA Stabilization Internal N(7)-methylguanine-containing RNA Reader Activity Nucleobase-containing Compound Metabolic Process RNA Processing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Stress Granule Assembly Myofibroblast Contraction Negative Regulation Of RNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process Signal Transduction By P53 Class Mediator Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA 3'-UTR Binding Spliceosome-depend Formation Of Circular RNA Pre-mRNA 5'-splice Site Binding Selenocysteine Insertion Sequence Binding Commitment Complex Signal Transduction In Response To DNA Damage Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of RNA Splicing Regulation Of MRNA Stability Germ Cell Development Microglia Differentiation Negative Regulation Of Macrophage Differentiation Spliceosomal Complex MRNA 5'-splice Site Recognition Selenocysteine Incorporation Monoubiquitinated Protein Deubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Organelle Assembly Regulation Of RNA Stability Regulation Of Stress Granule Assembly Intracellular MRNA Localization	Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Nervous System Process Positive Regulation Of Myelination Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Myelination Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Internal N(7)-methylguanine-containing RNA Reader Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Translation Regulation Of Protein Import Regulation Of MiRNA Metabolic Process Regulation Of Gene Expression Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Biosynthetic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Myofibroblast Contraction Regulation Of Gliogenesis Negative Regulation Of MiRNA Catabolic Process Positive Regulation Of Base-excision Repair DUBm Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response
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