DUSP23 and MKRN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DUSP23	MKRN1
Gene Name		dual specificity phosphatase 23	makorin ring finger protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Extracellular Vesicular Exosome	Cellular_component
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Protein-Protein Interactions		24 interactors: ASB13 CCDC186 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 KIAA1377 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746	7 interactors: CSNK1G1 DUSP23 EXOSC8 FADD MAP1LC3B UBE2D3 UBE2W
Entrez ID		54935	23608
HPRD ID		07908	09673
Ensembl ID		ENSG00000158716	ENSG00000133606
Uniprot IDs		Q9BVJ7	Q9UHC7
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Organelle Organization Regulation Of Gene Expression By Genetic Imprinting Gene Expression Genetic Imprinting Positive Regulation Of Histone Methylation Negative Regulation Of Male Germ Cell Proliferation Regulation Of Histone Methylation Positive Regulation Of Protein Modification Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Regulation Of Male Germ Cell Proliferation Dihydrobiopterin Metabolic Process Cell Communication By Chemical Coupling S-adenosylmethioninamine Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization	Protein K11-linked Ubiquitination Protein Monoubiquitination TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Toll-like Receptor Signaling Pathway Motor Neuron Apoptotic Process Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRAIL-activated Apoptotic Signaling Pathway Catabolic Process Protein Polyubiquitination Positive Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Necroptotic Signaling Pathway Positive Regulation Of Cellular Extravasation Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Macrophage Differentiation Negative Regulation Of Activation-induced Cell Death Of T Cells Positive Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Activation-induced Cell Death Of T Cells Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Negative Regulation Of Necroptotic Process Response To Misfolded Protein Cellular Response To Nitrogen Starvation Lymph Node Development Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Positive Regulation Of T Cell Migration Regulation Of T Cell Migration Nucleophagy Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Activated T Cell Proliferation Regulation Of Necrotic Cell Death Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Stress Immune Response-regulating Signaling Pathway Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Protein Modification Process Negative Regulation Of T Cell Apoptotic Process Mitochondrion Degradation
Tagcloud ?			apathogenic aspects cap circovirus gc1qr genotypes hsp40 hybrid immunofluorescence interacting lifecycle localisation nap1 npm1 others overlapping par pathogen pcv pcv1 pcv2 porcine prominent redistribution rep swine tdg vg5q znf265
Tagcloud (Difference) ?			apathogenic aspects cap circovirus gc1qr genotypes hsp40 hybrid immunofluorescence interacting lifecycle localisation nap1 npm1 others overlapping par pathogen pcv pcv1 pcv2 porcine prominent redistribution rep swine tdg vg5q znf265
Tagcloud (Intersection) ?