DUSP23 and TMOD3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		DUSP23	TMOD3
Description		dual specificity phosphatase 23	tropomodulin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Cytoskeleton Striated Muscle Thin Filament Adherens Junction Myofibril
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity	Actin Binding Protein Binding Tropomyosin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Dephosphorylation Cilium Assembly	Muscle Contraction Actin Filament Organization Actin Cytoskeleton Organization Myofibril Assembly Mitotic Cell Cycle Phase Transition Erythrocyte Development Pointed-end Actin Filament Capping Cell-cell Adhesion Positive Regulation Of Mitotic Cell Cycle Phase Transition
Pathways			Striated Muscle Contraction RHOBTB2 GTPase cycle RND3 GTPase cycle
Drugs		4-Nitrophenyl Phosphate
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746	5 interacting genes: CDC42 CSNK2A1 DUSP23 MAP1LC3B TNFSF11
Entrez ID		54935	29766
HPRD ID		07908	10389
Ensembl ID		ENSG00000158716	ENSG00000138594
Uniprot IDs		A0A140VJI5 Q9BVJ7	Q9NYL9
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cell Growth Mononuclear Cell Migration Apolipoprotein A-I Receptor Binding Endothelin Receptor Signaling Pathway Involved In Heart Process Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Myeloid Leukocyte Differentiation Negative Regulation Of Proteolysis Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Macroautophagy Negative Regulation Of Protein Catabolic Process Organelle Assembly Viral Translation Negative Regulation Of Nerve Growth Factor Production Viral Life Cycle Golgi Apparatus Subcompartment Regulation Of Nerve Growth Factor Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Dibasic Protein Processing Organelle Membrane Zymogen Inhibition Nerve Growth Factor Production Regulation Of Lipid Transport Negative Regulation Of Receptor Catabolic Process Negative Regulation Of Neurotrophin Production Tooth Eruption Positive Regulation Of Osteoclast Development Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of Aggrephagy Cytokine Precursor Processing Nerve Growth Factor Binding Osteoclast Proliferation Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cell Surface Receptor Signaling Pathway Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Fever Generation Osteoclast Development Paracrine Signaling Tumor Necrosis Factor Receptor Superfamily Binding Leukocyte Migration
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