DUSP23 and CCDC186

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DUSP23	CCDC186
Gene Name		dual specificity phosphatase 23	coiled-coil domain containing 186
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Protein-Protein Interactions		24 interactors: ASB13 CCDC186 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 KIAA1377 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746	2 interactors: DUSP23 PLEKHA5
Entrez ID		54935	55088
HPRD ID		07908	16576
Ensembl ID		ENSG00000158716	ENSG00000165813
Uniprot IDs		Q9BVJ7	Q7Z3E2
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Organelle Organization Regulation Of Gene Expression By Genetic Imprinting Gene Expression Genetic Imprinting Positive Regulation Of Histone Methylation Negative Regulation Of Male Germ Cell Proliferation Regulation Of Histone Methylation Positive Regulation Of Protein Modification Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Regulation Of Male Germ Cell Proliferation Dihydrobiopterin Metabolic Process Cell Communication By Chemical Coupling S-adenosylmethioninamine Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization
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