DUSP23 and GCM1

Number of citations of the paper that reports this interaction (PMID 20855292)
3

Data Source:
BioGRID (enzymatic study)

		DUSP23	GCM1
Gene Name		dual specificity phosphatase 23	glial cells missing homolog 1 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Extracellular Vesicular Exosome	Nucleus Transcription Factor Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Zinc Ion Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Fate Commitment Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Branching Involved In Labyrinthine Layer Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development
Pathways
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Protein-Protein Interactions		24 interactors: ASB13 CCDC186 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 KIAA1377 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746	9 interactors: CAMK1 CREBBP DUSP23 HDAC1 HDAC3 HDAC4 HDAC5 SENP1 UBE2I
Entrez ID		54935	8521
HPRD ID		07908	04757
Ensembl ID		ENSG00000158716	ENSG00000137270
Uniprot IDs		Q9BVJ7	Q9NP62
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Organelle Organization Regulation Of Gene Expression By Genetic Imprinting Gene Expression Genetic Imprinting Positive Regulation Of Histone Methylation Negative Regulation Of Male Germ Cell Proliferation Regulation Of Histone Methylation Positive Regulation Of Protein Modification Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Regulation Of Male Germ Cell Proliferation Dihydrobiopterin Metabolic Process Cell Communication By Chemical Coupling S-adenosylmethioninamine Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization	Histone H4 Deacetylation Histone H3 Deacetylation Histone H3-K9 Modification Histone Deacetylation Protein Deacetylation Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Notch Signaling Pathway Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Protein Metabolic Process Negative Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Myotube Differentiation Chromosome Organization Regulation Of Skeletal Muscle Fiber Development Regulation Of Protein Binding Regulation Of Muscle Cell Differentiation Negative Regulation Of Striated Muscle Cell Differentiation Chromatin Remodeling Osteoblast Development Protein Sumoylation Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Binding Regulation Of Cell Differentiation Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Myotube Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Difference) ?			blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Intersection) ?