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PTN and SPIN1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
PTN
SPIN1
Gene Name
pleiotrophin
spindlin 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Endoplasmic Reticulum
Nucleus
Nucleolus
Spindle
Molecular Function
Protein Phosphatase Inhibitor Activity
Growth Factor Activity
Heparin Binding
Protein Binding
Methylated Histone Binding
Biological Process
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Nervous System Development
Learning
Positive Regulation Of Cell Proliferation
Bone Mineralization
Negative Regulation Of Catalytic Activity
Positive Regulation Of Cell Division
Multicellular Organismal Development
Gamete Generation
RRNA Transcription
Wnt Signaling Pathway
Chromatin Modification
Positive Regulation Of Wnt Signaling Pathway
Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Height (
20881960
18391951
)
Protein-Protein Interactions
97 interactors:
ACTB
ALK
APOBEC3G
ARIH2
ARL15
ATP5C1
ATRX
BAG6
BARD1
BCCIP
BCL2L1
BLOC1S1
BMI1
BTBD2
C11orf58
C7orf25
CAAP1
CACNB4
CAPZB
CCDC53
CDH10
CDK5RAP2
CGA
CHD3
COX6C
CRCT1
CRELD1
CSTA
CYP2E1
DFNA5
DNAJB11
DUSP12
EIF3F
EVA1A
FEZ1
FTL
GADD45A
GADD45G
GIPC2
GLYAT
GNB2L1
GPD1
GPRASP2
GSK3B
GSTP1
GTF2F1
HGH1
HSPBAP1
ITSN2
KPNB1
LAMA4
LUC7L2
MAD2L1BP
MKKS
MLLT3
MRPL44
MYCBP
NAP1L5
NCAN
NEK6
NUDT21
P4HB
PFDN1
PIAS4
PLXNB2
PMF1
PPP2CA
PSMB10
PSMD11
PSMD2
PTPRS
PTPRZ1
RBM23
RIT1
RPLP1
SAT1
SDC1
SDC3
SGSM2
SGTA
SLC25A36
SNCAIP
SPIN1
SSR1
STC2
SUPT7L
TAC3
TAF1D
TBRG4
TOMM20
TP53BP2
TSC22D1
TXNDC9
UBQLN1
UBQLN4
UTP3
WFDC2
2 interactors:
PRMT6
PTN
Entrez ID
5764
10927
HPRD ID
01199
18096
Ensembl ID
ENSG00000105894
ENSG00000106723
Uniprot IDs
P21246
Q9Y657
PDB IDs
2NS2
4H75
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Nitrogen Compound Metabolic Process
Apoptotic Process
Central Nervous System Development
Regulation Of Cellular Protein Metabolic Process
Cellular Metabolic Process
Programmed Cell Death
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Cell Death
Regulation Of Cell Cycle
Death
Regulation Of Protein Catabolic Process
Negative Regulation Of Transferase Activity
Response To Endoplasmic Reticulum Stress
Regulation Of Cell Death
Regulation Of Cellular Process
Signal Transduction By P53 Class Mediator
Cell Cycle Process
Negative Regulation Of Cell Cycle
Positive Regulation Of Transferase Activity
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Brain Development
Nervous System Development
Regulation Of Intrinsic Apoptotic Signaling Pathway
Signal Transduction In Response To DNA Damage
Positive Regulation Of Protein Modification Process
Viral Process
Developmental Process
Head Development
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Signal Transduction
Multicellular Organismal Development
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cellular Process
Heterocycle Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Metabolic Process
Anatomical Structure Development
Regulation Of Signaling
Cellular Response To Stress
Regulation Of Catalytic Activity
Negative Regulation Of Catalytic Activity
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Catalytic Activity
Histone H3-R2 Methylation
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Histone H4-R3 Methylation
Peptidyl-arginine N-methylation
Histone Arginine Methylation
Peptidyl-arginine Methylation
Bone Mineralization
Tagcloud
?
04fmolt4
04mg
09mg
28ng
32ng
37g
58vo2ml
64g
71ng
94ng
99mg
backgrounds
bat
carioca
chf
corticosterone
ctrl
d2
depot
endocrine
epididymal
freezing
glycemia
impair
kg0
retroperitoneal
t4
triglycerides
weights
Tagcloud (Difference)
?
04fmolt4
04mg
09mg
28ng
32ng
37g
58vo2ml
64g
71ng
94ng
99mg
backgrounds
bat
carioca
chf
corticosterone
ctrl
d2
depot
endocrine
epididymal
freezing
glycemia
impair
kg0
retroperitoneal
t4
triglycerides
weights
Tagcloud (Intersection)
?