PTN and APOBEC3G

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTN	APOBEC3G
Gene Name		pleiotrophin	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Ribonucleoprotein Complex Apolipoprotein B MRNA Editing Enzyme Complex
	Molecular Function	Protein Phosphatase Inhibitor Activity Growth Factor Activity Heparin Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Deoxycytidine Deaminase Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Nervous System Development Learning Positive Regulation Of Cell Proliferation Bone Mineralization Negative Regulation Of Catalytic Activity Positive Regulation Of Cell Division	Positive Regulation Of Defense Response To Virus By Host Cytidine Deamination Negative Regulation Of Transposition Viral Process Base Conversion Or Substitution Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Viral Process Defense Response To Virus DNA Cytosine Deamination
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		97 interactors: ACTB ALK APOBEC3G ARIH2 ARL15 ATP5C1 ATRX BAG6 BARD1 BCCIP BCL2L1 BLOC1S1 BMI1 BTBD2 C11orf58 C7orf25 CAAP1 CACNB4 CAPZB CCDC53 CDH10 CDK5RAP2 CGA CHD3 COX6C CRCT1 CRELD1 CSTA CYP2E1 DFNA5 DNAJB11 DUSP12 EIF3F EVA1A FEZ1 FTL GADD45A GADD45G GIPC2 GLYAT GNB2L1 GPD1 GPRASP2 GSK3B GSTP1 GTF2F1 HGH1 HSPBAP1 ITSN2 KPNB1 LAMA4 LUC7L2 MAD2L1BP MKKS MLLT3 MRPL44 MYCBP NAP1L5 NCAN NEK6 NUDT21 P4HB PFDN1 PIAS4 PLXNB2 PMF1 PPP2CA PSMB10 PSMD11 PSMD2 PTPRS PTPRZ1 RBM23 RIT1 RPLP1 SAT1 SDC1 SDC3 SGSM2 SGTA SLC25A36 SNCAIP SPIN1 SSR1 STC2 SUPT7L TAC3 TAF1D TBRG4 TOMM20 TP53BP2 TSC22D1 TXNDC9 UBQLN1 UBQLN4 UTP3 WFDC2	4 interactors: APOBEC3F APP PRKACA PTN
Entrez ID		5764	60489
HPRD ID		01199	06172
Ensembl ID		ENSG00000105894	ENSG00000239713
Uniprot IDs		P21246	Q9HC16
PDB IDs			2JYW 2KBO 2KEM 3E1U 3IQS 3IR2 3V4J 3V4K
Enriched GO Terms of Interacting Partners?		Cell Cycle Nitrogen Compound Metabolic Process Apoptotic Process Central Nervous System Development Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Cell Death Regulation Of Cell Cycle Death Regulation Of Protein Catabolic Process Negative Regulation Of Transferase Activity Response To Endoplasmic Reticulum Stress Regulation Of Cell Death Regulation Of Cellular Process Signal Transduction By P53 Class Mediator Cell Cycle Process Negative Regulation Of Cell Cycle Positive Regulation Of Transferase Activity Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Brain Development Nervous System Development Regulation Of Intrinsic Apoptotic Signaling Pathway Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Modification Process Viral Process Developmental Process Head Development Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Process Heterocycle Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Signaling Cellular Response To Stress Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity	Negative Regulation Of Catalytic Activity Positive Regulation Of Mitotic Cell Cycle Innate Immune Response Positive Regulation Of Dense Core Granule Biogenesis Learning Regulation Of Protein Binding Cell Maturation Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Positive Regulation Of Cell Cycle Process Immune Response Defense Response Regulation Of Binding Learning Or Memory DNA Cytosine Deamination Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Cell Cycle Cognition Cellular Calcium Ion Homeostasis Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Calcium Ion Homeostasis Peptidyl-serine Autophosphorylation Base Conversion Or Substitution Editing Axon Choice Point Recognition Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Response To Light Stimulus Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transposition DNA Deamination Cytidine Deamination Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Desmosome Assembly Neuron Remodeling Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Tight Junction Assembly Regulation Of Protein Processing Cellular Metal Ion Homeostasis Response To External Stimulus Regulation Of Mitotic Cell Cycle Negative Regulation Of Glucose Import
Tagcloud ?		04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights	7sl a3f a3g assortment cytidine deaminases deltanc divergent editing encapsidate encapsidation engage exploit gag grna hv iclip incompletely indiscriminate nc nucleocapsid packaged packaging retroviral rnas unbiased virions
Tagcloud (Difference) ?		04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights	7sl a3f a3g assortment cytidine deaminases deltanc divergent editing encapsidate encapsidation engage exploit gag grna hv iclip incompletely indiscriminate nc nucleocapsid packaged packaging retroviral rnas unbiased virions
Tagcloud (Intersection) ?