ATRX and PTN

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATRX	PTN
Gene Name		alpha thalassemia/mental retardation syndrome X-linked	pleiotrophin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Heterochromatin PML Body Telomeric Heterochromatin SWI/SNF Superfamily-type Complex	Extracellular Space Endoplasmic Reticulum
	Molecular Function	DNA Binding DNA Helicase Activity Chromatin Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding DNA Translocase Activity Methylated Histone Binding Histone Binding Chromo Shadow Domain Binding	Protein Phosphatase Inhibitor Activity Growth Factor Activity Heparin Binding
	Biological Process	DNA Repair DNA Methylation DNA Recombination Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Positive Regulation Of Nuclear Cell Cycle DNA Replication DNA Damage Response, Signal Transduction By P53 Class Mediator Forebrain Development Replication Fork Processing Positive Regulation Of Telomere Maintenance DNA Duplex Unwinding Positive Regulation Of Transcription From RNA Polymerase II Promoter Sertoli Cell Development Seminiferous Tubule Development Cellular Response To Hydroxyurea Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter	Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Nervous System Development Learning Positive Regulation Of Cell Proliferation Bone Mineralization Negative Regulation Of Catalytic Activity Positive Regulation Of Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ATN1 BLM CALM1 CCSER2 DAXX EZH2 HDAC1 HDAC4 HIST1H3A HIST2H3C KIAA1377 LUC7L2 NEK1 NSD1 PTN PTPN4 RAD51 SVIL WRN ZBED1 ZNF512B	97 interactors: ACTB ALK APOBEC3G ARIH2 ARL15 ATP5C1 ATRX BAG6 BARD1 BCCIP BCL2L1 BLOC1S1 BMI1 BTBD2 C11orf58 C7orf25 CAAP1 CACNB4 CAPZB CCDC53 CDH10 CDK5RAP2 CGA CHD3 COX6C CRCT1 CRELD1 CSTA CYP2E1 DFNA5 DNAJB11 DUSP12 EIF3F EVA1A FEZ1 FTL GADD45A GADD45G GIPC2 GLYAT GNB2L1 GPD1 GPRASP2 GSK3B GSTP1 GTF2F1 HGH1 HSPBAP1 ITSN2 KPNB1 LAMA4 LUC7L2 MAD2L1BP MKKS MLLT3 MRPL44 MYCBP NAP1L5 NCAN NEK6 NUDT21 P4HB PFDN1 PIAS4 PLXNB2 PMF1 PPP2CA PSMB10 PSMD11 PSMD2 PTPRS PTPRZ1 RBM23 RIT1 RPLP1 SAT1 SDC1 SDC3 SGSM2 SGTA SLC25A36 SNCAIP SPIN1 SSR1 STC2 SUPT7L TAC3 TAF1D TBRG4 TOMM20 TP53BP2 TSC22D1 TXNDC9 UBQLN1 UBQLN4 UTP3 WFDC2
Entrez ID		546	5764
HPRD ID		02069	01199
Ensembl ID		ENSG00000085224	ENSG00000105894
Uniprot IDs		A4LAA3 B4DLW1 P46100	P21246
PDB IDs		2JM1 2LBM 2LD1 3QL9 3QLA 3QLC 3QLN
Enriched GO Terms of Interacting Partners?		Organelle Organization Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Cellular Response To Camptothecin Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Response To Camptothecin Cellular Response To Radiation Response To Ionizing Radiation Negative Regulation Of Gene Expression Cellular Response To Ionizing Radiation Nucleobase-containing Compound Metabolic Process DNA Methylation Chromatin Organization Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Radiation DNA Duplex Unwinding DNA Geometric Change Response To Stress Cellular Nitrogen Compound Metabolic Process DNA Methylation On Cytosine DNA Modification Regulation Of Cell Division Chromatin Silencing At RDNA Replication Fork Processing Positive Regulation Of Protein Serine/threonine Kinase Activity Cell Cycle DNA-dependent DNA Replication Chromatin Modification Wound Healing Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cell Cycle Process Histone H4 Deacetylation DNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Response To Wounding Gene Expression Double-strand Break Repair Histone Modification	Cell Cycle Nitrogen Compound Metabolic Process Apoptotic Process Central Nervous System Development Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Cell Death Regulation Of Cell Cycle Death Regulation Of Protein Catabolic Process Negative Regulation Of Transferase Activity Response To Endoplasmic Reticulum Stress Regulation Of Cell Death Regulation Of Cellular Process Signal Transduction By P53 Class Mediator Cell Cycle Process Negative Regulation Of Cell Cycle Positive Regulation Of Transferase Activity Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Brain Development Nervous System Development Regulation Of Intrinsic Apoptotic Signaling Pathway Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Modification Process Viral Process Developmental Process Head Development Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Process Heterocycle Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Signaling Cellular Response To Stress Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity
Tagcloud ?		12v2 altering banding beadchip bon constitution cytosnp exome frameshift gtg heterozygosity hiseq homozygous ilumina implicating indels lubrication muc neuroendocrine ngs nras ploidy pnet qgp sanger sequenced snvs stretches toolkit	04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights
Tagcloud (Difference) ?		12v2 altering banding beadchip bon constitution cytosnp exome frameshift gtg heterozygosity hiseq homozygous ilumina implicating indels lubrication muc neuroendocrine ngs nras ploidy pnet qgp sanger sequenced snvs stretches toolkit	04fmolt4 04mg 09mg 28ng 32ng 37g 58vo2ml 64g 71ng 94ng 99mg backgrounds bat carioca chf corticosterone ctrl d2 depot endocrine epididymal freezing glycemia impair kg0 retroperitoneal t4 triglycerides weights
Tagcloud (Intersection) ?