POU1F1 and NR1I3

Number of citations of the paper that reports this interaction (PMID 11891224)
3

Data Source:
HPRD (in vitro)

		POU1F1	NR1I3
Gene Name		POU class 1 homeobox 1	nuclear receptor subfamily 1, group I, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Coactivator Activity Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Androgen Receptor Activity Thyroid Hormone Receptor Activity Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Fate Specification Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Determination Of Adult Lifespan B Cell Differentiation Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Positive Regulation Of Multicellular Organism Growth Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Transport Somatotropin Secreting Cell Development	Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Gene Expression Androgen Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CREBBP ETS1 GATA2 JUN NCOR1 NR1I2 NR1I3 NR3C1 PITX1 PPARA PPARG VDR	18 interactors: CHD9 EIF3I FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC
Entrez ID		5449	9970
HPRD ID		01409	04858
Ensembl ID		ENSG00000064835	ENSG00000143257
Uniprot IDs		P28069	E9PB75 E9PC13 E9PDU3 E9PHC8 F1DAL4 Q14994 Q6GZ76 Q6GZ79 Q6GZ82 Q6GZ89
PDB IDs			1XV9 1XVP
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Steroid Hormone Negative Regulation Of Gene Expression Response To Lipid Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Gland Development Diencephalon Development Response To Hormone Cellular Response To Hormone Stimulus Response To Organic Substance	Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression Androgen Receptor Signaling Pathway Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Response To Hormone Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Cellular Biosynthetic Process DNA-templated Transcription, Initiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Response To Steroid Hormone Gland Development Response To Lipid Response To Organic Cyclic Compound RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Development Branching Involved In Mammary Gland Duct Morphogenesis Mammary Gland Branching Involved In Thelarche Peroxisome Proliferator Activated Receptor Signaling Pathway Cellular Response To Organic Cyclic Compound Developmental Process Involved In Reproduction Placenta Development Small Molecule Metabolic Process Biosynthetic Process Regulation Of Signaling Regulation Of Gene Expression Mammary Gland Duct Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Lipid Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Reproductive Structure Development Reproductive System Development In Utero Embryonic Development Regulation Of Metabolic Process Cellular Response To Thyroid Hormone Stimulus
Tagcloud ?		ago architectural architecture artificial bypassing developmentally enhancer enhancers exemplified homeodomain matrin naturally occupied otherwise pit1 r271w ref requisite rescued restores satb1 serves subnuclear tethered tethering unanticipated unexpectedly untethered	26s activators anchored androstane car carbaldehyde chlorophenyl citco cytosol dichlorobenzyl disrupting disrupts gal1 hcar held hepatocytes homoeostasis imidazo oxime paradoxically phenobarbital proteasomal quiescent repressing sug1 tethering thiazole ubiquitinated xenobiotic
Tagcloud (Difference) ?		ago architectural architecture artificial bypassing developmentally enhancer enhancers exemplified homeodomain matrin naturally occupied otherwise pit1 r271w ref requisite rescued restores satb1 serves subnuclear tethered unanticipated unexpectedly untethered	26s activators anchored androstane car carbaldehyde chlorophenyl citco cytosol dichlorobenzyl disrupting disrupts gal1 hcar held hepatocytes homoeostasis imidazo oxime paradoxically phenobarbital proteasomal quiescent repressing sug1 thiazole ubiquitinated xenobiotic
Tagcloud (Intersection) ?		tethering