KRT20 and ABI2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT20	ABI2
Gene Name		keratin 20, type I	abl-interactor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intermediate Filament	Cytoplasm Cytosol Cytoskeleton Lamellipodium Filopodium SCAR Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Rac GTPase Binding Proline-rich Region Binding
	Biological Process	Apoptotic Process Cellular Response To Stress Intermediate Filament Organization Regulation Of Protein Secretion	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Actin Polymerization Or Depolymerization Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Height ( 19893584)	Butyrylcholinesterase levels ( 21862451) Subclinical atherosclerosis traits (other) ( 17903303)
Protein-Protein Interactions		27 interactors: ABI2 AMOTL2 ANKRD36BP1 C9orf16 CCDC85B COASY EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT40 KRT80 KRTAP10-7 KRTAP10-8 KRTAP10-9 NOTCH2NL NUP62 PIK3R2 PLEKHA5 PRC1 TFIP11 TXLNA USHBP1 VIM ZC2HC1C ZC3H14	57 interactors: ABL1 ADAM19 AES ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCDC36 CCDC53 CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MRFAP1L1 MRPL44 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SNAP23 STAM2 TFIP11 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WIPF1
Entrez ID		54474	10152
HPRD ID		12193	07338
Ensembl ID		ENSG00000171431	ENSG00000138443
Uniprot IDs		P35900	E9PEZ7 Q9NYB9
PDB IDs			2ED0 3P8C
Enriched GO Terms of Interacting Partners?			Intracellular Transport Organelle Organization Cell Projection Assembly Establishment Of Localization In Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Stimulus Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Negative Regulation Of Signaling Cellular Localization Cellular Component Assembly Regulation Of Signal Transduction Cell Projection Morphogenesis Cellular Response To Stimulus Developmental Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Cell Cycle Arrest Cell Projection Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Actin Cytoskeleton Organization System Development Actin Filament-based Process Anatomical Structure Development Signaling Intraciliary Transport Cell Morphogenesis Membrane Organization Generation Of Neurons Cell Communication Regulation Of Autophagy Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Protein Localization Protein Transport Neurogenesis Lamellipodium Assembly Signal Transduction Lamellipodium Organization Establishment Of Protein Localization Negative Regulation Of Cellular Senescence Microtubule-based Transport
Tagcloud ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning gast grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Difference) ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning gast grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Intersection) ?