KRT20 and EXOC8

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		KRT20	EXOC8
Description		keratin 20	exocyst complex component 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Projection Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Small GTPase Binding Phosphatidylinositol Binding
	Biological Process	Morphogenesis Of An Epithelium Apoptotic Process Cellular Response To Starvation Epithelial Cell Differentiation Intermediate Filament Organization Regulation Of Protein Secretion	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Endosome Organization Intracellular Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways		Keratinization Formation of the cornified envelope	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Height ( 19893584)	Hemoglobin concentration ( 27863252)
Interacting Genes		45 interacting genes: ABI2 AMOTL2 ANKRD36BP1 BBLN BCAS2 CCDC196 CCDC85B COASY CYSRT1 DES EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT24 KRT27 KRT3 KRT31 KRT34 KRT40 KRT72 KRT75 KRT80 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP6-3 NOTCH2NLA NUP62 PIK3R2 PLEKHA5 PPP1R13B PRC1 PRPH SNAPIN TFIP11 TXLNA USHBP1 VIM WASHC1 ZC2HC1C ZC3H14	88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4
Entrez ID		54474	149371
HPRD ID		12193	09943
Ensembl ID		ENSG00000171431	ENSG00000116903
Uniprot IDs		P35900	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Cytoskeleton Organization Structural Molecule Activity Organelle Organization Cytosol Cytoskeleton Keratinization Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Protein Binding Epidermis Development Cell Differentiation Developmental Process Exocyst	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Protein Binding Supramolecular Fiber Organization Intermediate Filament Organelle Organization Structural Molecule Activity Negative Regulation Of Viral Transcription Cytoskeleton Regulation Of Viral Transcription Regulation Of Post-translational Protein Modification Regulation Of Protein Autoubiquitination Molecular Adaptor Activity Cytoskeleton Organization Identical Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity Cellular Localization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Lysosome Size BORC Complex Post-mRNA Release Spliceosomal Complex Gamma-tubulin Binding Autophagosome Epidermis Development
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