SNTG2 and DMD

Number of citations of the paper that reports this interaction (PMID 10747910)
24

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SNTG2	DMD
Gene Name		syntrophin, gamma 2	dystrophin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Syntrophin Complex Sarcolemma	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane
	Molecular Function	Actin Binding PDZ Domain Binding	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding
	Biological Process	Central Nervous System Development	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS			Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		6 interactors: BAI1 DMD DTNA DTNB MPP3 SCN5A	27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN
Entrez ID		54221	1756
HPRD ID		16374	02303
Ensembl ID		ENSG00000172554	ENSG00000198947
Uniprot IDs		Q9NY99	A1L0U9 A7E212 P11532 Q16484 Q4G0X0
PDB IDs			1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Striated Muscle Contraction Muscle Contraction Muscle System Process Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Cardiac Muscle Contraction Regulation Of Sodium Ion Transport Heart Contraction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Peripheral Nervous System Development Establishment Of Glial Blood-brain Barrier Regulation Of Muscle Contraction Cell Projection Morphogenesis Regulation Of Ion Homeostasis Cell Part Morphogenesis Regulation Of Heart Contraction Cell-cell Signaling Negative Regulation Of Peptidyl-cysteine S-nitrosylation Membrane Depolarization During SA Node Cell Action Potential Positive Regulation Of Ion Transport Signaling Cell Morphogenesis Cell Communication SA Node Cell Action Potential Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier AV Node Cell To Bundle Of His Cell Communication Cell Projection Organization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Membrane Potential Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Olfactory Nerve Development Regulation Of Skeletal Muscle Contraction SA Node Cell To Atrial Cardiac Muscle Cell Communication Bundle Of His Cell To Purkinje Myocyte Communication Blood Circulation Neurotransmitter Receptor Metabolic Process Cellular Response To Stimulus Positive Regulation Of Action Potential Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Response To Denervation Involved In Regulation Of Muscle Adaptation Motile Cilium Assembly Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Response To Inactivity Generation Of Neurons	Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death
Tagcloud ?			2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Difference) ?			2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Intersection) ?