SNTG2 and ADGRB1

Number of citations of the paper that reports this interaction (PubMedID 23782696)
64

Data Source:
BioGRID (unspecified method)

		SNTG2	ADGRB1
Description		syntrophin gamma 2	adhesion G protein-coupled receptor B1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Sarcolemma	Phagocytic Cup Extracellular Region Extracellular Space Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Membrane Cell Junction Dendrite Cell Projection Dendritic Spine Synapse Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding PDZ Domain Binding Neuroligin Family Protein Binding	Lipopolysaccharide Binding Phosphatidylserine Binding Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding
	Biological Process	Central Nervous System Development	Immune System Process Phagocytosis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Nervous System Development Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Calcific aortic valve stenosis ( 32141789) Familial squamous cell lung carcinoma ( 29924316) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hypothyroidism ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Refractive error ( 32231278) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)	Bipolar disorder x sex interaction ( 34099189)
Interacting Genes		13 interacting genes: ADGRB1 BET1 DMD DTNA DTNB HACE1 MIPOL1 MPP3 PALS1 RPS6KA1 SCN5A VANGL2 VCPIP1	21 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 DRD2 ELMO1 ERBB2 GPR35 GPR37 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2
Entrez ID		54221	575
HPRD ID		16374	04062
Ensembl ID		ENSG00000172554	ENSG00000181790
Uniprot IDs		Q9NY99	A0A2R8Y5M7 O14514
PDB IDs		7QQL
Enriched GO Terms of Interacting Partners?		PDZ Domain Binding Striated Muscle Contraction Nitric-oxide Synthase Binding Lateral Plasma Membrane Membrane Organization Sarcolemma Cell Communication Golgi Organization Synaptic Signaling Anchoring Junction Membrane Fusion Neuron Development Cell-cell Junction Synapse Regulation Of Sodium Ion Transmembrane Transport Muscle Contraction Cardiac Muscle Cell Action Potential Cardiac Muscle Contraction Voltage-gated Sodium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Sodium Channel Activity Involved In Purkinje Myocyte Action Potential Voltage-gated Sodium Channel Activity Involved In Bundle Of His Cell Action Potential Voltage-gated Sodium Channel Activity Involved In SA Node Cell Action Potential Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Myelin Sheath Abaxonal Region Muscle System Process Cell-cell Signaling Signaling Regulation Of Sodium Ion Transport Bundle Of His Cell Action Potential Membrane Depolarization During Bundle Of His Cell Action Potential Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Establishment Of Planar Polarity Involved In Neural Tube Closure Cell Pole Cell Migration Involved In Kidney Development Lateral Sprouting Involved In Lung Morphogenesis Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Regulation Of Cardiac Muscle Contraction Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Depolarization During Purkinje Myocyte Cell Action Potential Serotonergic Neuron Axon Guidance Convergent Extension Involved In Neural Plate Elongation Dopaminergic Neuron Axon Guidance Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Apical Plasma Membrane Regulation Of Striated Muscle Contraction Regulation Of Heart Rate Syntrophin Complex	PDZ Domain Binding Plasma Membrane Dystrophin-associated Glycoprotein Complex Protein Localization To Synapse Bicellular Tight Junction Anchoring Junction Protein Localization To Cell Junction Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Cell-cell Junction Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Synapse Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein-containing Complex Localization Neuromuscular Junction Adherens Junction Cell Junction L27 Domain Binding Beta-1 Adrenergic Receptor Binding Ionotropic Glutamate Receptor Binding Syntrophin Complex Sarcolemma Postsynaptic Density MPP7-DLG1-LIN7 Complex Neuroligin Family Protein Binding Membrane Protein Localization To Membrane Cytoplasm Establishment Or Maintenance Of Cell Polarity GMP Kinase Activity Structural Molecule Activity Synaptic Membrane Lateral Plasma Membrane Peristalsis GDP Metabolic Process Regulation Of Sodium Ion Transport Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Muscle Contraction Regulation Of Receptor Internalization Regulation Of Behavior Intracellular Protein Localization Protein Localization To Cell Periphery Regulation Of Membrane Potential Postsynaptic Membrane Presynapse Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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