SNTG2 and DTNA

Number of citations of the paper that reports this interaction (PMID 10747910)
24

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SNTG2	DTNA
Gene Name		syntrophin, gamma 2	dystrobrevin, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Syntrophin Complex Sarcolemma	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Sarcolemma Protein Complex Synapse
	Molecular Function	Actin Binding PDZ Domain Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Central Nervous System Development	Striated Muscle Contraction Signal Transduction Synaptic Transmission Neuromuscular Synaptic Transmission
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: BAI1 DMD DTNA DTNB MPP3 SCN5A	14 interactors: ACTA1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 SYNC SYNM UTRN
Entrez ID		54221	1837
HPRD ID		16374	03141
Ensembl ID		ENSG00000172554	ENSG00000134769
Uniprot IDs		Q9NY99	A8K541 B7Z3X3 M0QYX6 Q9Y4J8
PDB IDs			2E5R
Enriched GO Terms of Interacting Partners?		Striated Muscle Contraction Muscle Contraction Muscle System Process Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Cardiac Muscle Contraction Regulation Of Sodium Ion Transport Heart Contraction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Peripheral Nervous System Development Establishment Of Glial Blood-brain Barrier Regulation Of Muscle Contraction Cell Projection Morphogenesis Regulation Of Ion Homeostasis Cell Part Morphogenesis Regulation Of Heart Contraction Cell-cell Signaling Negative Regulation Of Peptidyl-cysteine S-nitrosylation Membrane Depolarization During SA Node Cell Action Potential Positive Regulation Of Ion Transport Signaling Cell Morphogenesis Cell Communication SA Node Cell Action Potential Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier AV Node Cell To Bundle Of His Cell Communication Cell Projection Organization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Membrane Potential Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Olfactory Nerve Development Regulation Of Skeletal Muscle Contraction SA Node Cell To Atrial Cardiac Muscle Cell Communication Bundle Of His Cell To Purkinje Myocyte Communication Blood Circulation Neurotransmitter Receptor Metabolic Process Cellular Response To Stimulus Positive Regulation Of Action Potential Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Response To Denervation Involved In Regulation Of Muscle Adaptation Motile Cilium Assembly Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Response To Inactivity Generation Of Neurons	Muscle Contraction Muscle System Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Myotube Cell Development Actin-myosin Filament Sliding Muscle Filament Sliding Cardiac Muscle Cell Action Potential Intermediate Filament-based Process Actin-mediated Cell Contraction Muscle Fiber Development Positive Regulation Of Cell-matrix Adhesion Muscle Organ Development Myotube Differentiation Actin Filament-based Movement Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Muscle Structure Development Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development System Development Regulation Of Muscle Contraction Striated Muscle Cell Development Synaptic Transmission Regulation Of Dopamine Receptor Signaling Pathway Skeletal Muscle Thin Filament Assembly Olfactory Nerve Development Muscle Cell Development Regulation Of Skeletal Muscle Contraction Actin Filament-based Process Skeletal Myofibril Assembly Neurotransmitter Receptor Metabolic Process Regulation Of Cell-substrate Adhesion Platelet Dense Granule Organization
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