SNTG2 and DTNA

Number of citations of the paper that reports this interaction (PubMedID 10747910)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SNTG2	DTNA
Description		syntrophin gamma 2	dystrobrevin alpha
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Sarcolemma	Nucleoplasm Cytoplasm Plasma Membrane Membrane Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Cell Projection Intermediate Filament Cytoskeleton Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding PDZ Domain Binding Neuroligin Family Protein Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding Metal Ion Binding
	Biological Process	Central Nervous System Development	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Synaptic Signaling
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Calcific aortic valve stenosis ( 32141789) Familial squamous cell lung carcinoma ( 29924316) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hypothyroidism ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Refractive error ( 32231278) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) PR interval ( 32439900) Urate levels in overweight individuals ( 25811787)
Interacting Genes		13 interacting genes: ADGRB1 BET1 DMD DTNA DTNB HACE1 MIPOL1 MPP3 PALS1 RPS6KA1 SCN5A VANGL2 VCPIP1	16 interacting genes: ACTA1 APPL1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN
Entrez ID		54221	1837
HPRD ID		16374	03141
Ensembl ID		ENSG00000172554	ENSG00000134769
Uniprot IDs		Q9NY99	A0A7P0T9L1 A0A7P0TBH9 A0A7P0Z4D7 B7Z3X3 Q9Y4J8
PDB IDs		7QQL	2E5R
Enriched GO Terms of Interacting Partners?		PDZ Domain Binding Striated Muscle Contraction Nitric-oxide Synthase Binding Lateral Plasma Membrane Membrane Organization Sarcolemma Cell Communication Golgi Organization Synaptic Signaling Anchoring Junction Membrane Fusion Neuron Development Cell-cell Junction Synapse Regulation Of Sodium Ion Transmembrane Transport Muscle Contraction Cardiac Muscle Cell Action Potential Cardiac Muscle Contraction Voltage-gated Sodium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Sodium Channel Activity Involved In Purkinje Myocyte Action Potential Voltage-gated Sodium Channel Activity Involved In Bundle Of His Cell Action Potential Voltage-gated Sodium Channel Activity Involved In SA Node Cell Action Potential Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Myelin Sheath Abaxonal Region Muscle System Process Cell-cell Signaling Signaling Regulation Of Sodium Ion Transport Bundle Of His Cell Action Potential Membrane Depolarization During Bundle Of His Cell Action Potential Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Establishment Of Planar Polarity Involved In Neural Tube Closure Cell Pole Cell Migration Involved In Kidney Development Lateral Sprouting Involved In Lung Morphogenesis Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Regulation Of Cardiac Muscle Contraction Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Depolarization During Purkinje Myocyte Cell Action Potential Serotonergic Neuron Axon Guidance Convergent Extension Involved In Neural Plate Elongation Dopaminergic Neuron Axon Guidance Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Apical Plasma Membrane Regulation Of Striated Muscle Contraction Regulation Of Heart Rate Syntrophin Complex	Dystrophin-associated Glycoprotein Complex Sarcolemma Syntrophin Complex Muscle Contraction Muscle System Process Actin Binding Vinculin Binding Structural Molecule Activity Cytoskeleton Regulation Of Sodium Ion Transmembrane Transport System Process Regulation Of Sodium Ion Transport Protein-containing Complex Filopodium Nitric-oxide Synthase Binding Neuromuscular Junction PDZ Domain Binding Plasma Membrane Costamere Structural Constituent Of Cytoskeleton Regulation Of Monoatomic Ion Transmembrane Transport Synapse Filopodium Membrane Myosin Binding Regulation Of Transport Positive Regulation Of Endocytosis Anchoring Junction Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Monoatomic Ion Transport Cardiac Muscle Cell Action Potential Structural Constituent Of Muscle Calmodulin Binding Regulation Of Heart Contraction Fast-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cytoplasm Postsynaptic Membrane Regulation Of Blood Circulation Lateral Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Postsynaptic Density Glutamatergic Synapse Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Neurofilament Cytoskeleton Positive Regulation Of Macropinocytosis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Actin Cytoskeleton Signaling Striated Muscle Contraction Cell Communication
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