SEPTIN5 and KIDINS220

Number of citations of the paper that reports this interaction (PubMedID 20680483)
0

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SEPTIN5	KIDINS220
Description		septin 5	kinase D interacting substrate 220
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Septin Complex Cell Division Site	Endosome Late Endosome Cytosol Membrane Protein-containing Complex
	Molecular Function	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Protein Binding Protein Kinase Regulator Activity PDZ Domain Binding
	Biological Process	Intracellular Protein Localization Synaptic Vesicle Targeting Regulation Of Exocytosis Adult Behavior Social Behavior Cell Division Cytoskeleton-dependent Cytokinesis Regulation Of Synaptic Vesicle Exocytosis	In Utero Embryonic Development Nervous System Development Positive Regulation Of Neuron Projection Development Nerve Growth Factor Signaling Pathway Dendrite Morphogenesis Cellular Response To Nerve Growth Factor Stimulus
Pathways			ARMS-mediated activation ARMS-mediated activation RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32109663) Neutrophil count ( 21507922) Skin aging measurement ( 31522824) Waist-hip ratio ( 28552196)
Interacting Genes		21 interacting genes: APP CDK5R1 DDIT4L KAT7 KIDINS220 LSM8 MAGEA2 MAGEA2B MAPK6 MYOG PFN2 PLEKHF2 PRKN SEPTIN1 SEPTIN2 SEPTIN4 SEPTIN7 SEPTIN8 SPG21 STX1A STX4	12 interacting genes: CDC73 CRKL FHL3 KRT34 MOB4 MYC NGFR NTRK1 NTRK2 NTRK3 PRKD1 SEPTIN5
Entrez ID		5413	57498
HPRD ID		04100	17235
Ensembl ID		ENSG00000184702	ENSG00000134313
Uniprot IDs		Q99719 X5DNA9	A0A8I5QJC0 Q9ULH0
PDB IDs		6WCU
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Sperm Annulus Cytoskeleton-dependent Cytokinesis Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Molecular Adaptor Activity Presynapse Axon Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Protein Ubiquitination Negative Regulation Of Protein Acetylation Microtubule Cytoskeleton Regulation Of Spontaneous Synaptic Transmission Synaptic Vesicle Positive Regulation Of Post-translational Protein Modification Modulation Of Excitatory Postsynaptic Potential Regulation Of Establishment Of Protein Localization GTPase Activity Cellular Response To Manganese Ion Neuron Projection Regulation Of Secretion By Cell Negative Regulation Of Protein Sumoylation Regulation Of Transport GTP Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Cell Projection Regulation Of Secretion Positive Regulation Of Protein Modification Process Regulation Of Protein Ubiquitination SNARE Complex Assembly Regulation Of Apoptotic Signaling Pathway Synapse Regulation Of Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Dopaminergic Synapse Regulation Of Amine Transport Response To Manganese Ion Intracellular Protein Localization Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Neurotransmitter Secretion Regulation Of Protein Transport Postsynapse Collateral Sprouting Cellular Response To Catecholamine Stimulus Regulation Of Post-translational Protein Modification Neurotransmitter Transport Schaffer Collateral - CA1 Synapse	Neurotrophin Binding Neurotrophin Receptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Response To Growth Factor Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signaling Neurotrophin Signaling Pathway Mechanoreceptor Differentiation Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Circadian Rhythm Cellular Developmental Process Positive Regulation Of Neuron Projection Development Cellular Response To Nerve Growth Factor Stimulus Regulation Of Signal Transduction Response To Nerve Growth Factor Nerve Growth Factor Binding Regulation Of Cell Population Proliferation Positive Regulation Of Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Neuron Projection Development GPI-linked Ephrin Receptor Activity Positive Regulation Of Synapse Assembly Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Oxygen-containing Compound Apoptotic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Postsynaptic Specialization Assembly Regulation Of Apoptotic Process Regulation Of Multicellular Organismal Development Action Potential Propagation Neuronal Action Potential Propagation Cell Death Programmed Cell Death Rhythmic Process B Cell Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Regulation Of Fibroblast Proliferation Nervous System Development System Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Developmental Process Positive Regulation Of Cell Junction Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization
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