PNN and RNPS1

Number of citations of the paper that reports this interaction (PubMedID 14517304)
49

Data Source:
HPRD (in vivo, in vitro)

		PNN	RNPS1
Description		pinin, desmosome associated protein	RNA binding protein with serine rich domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Anchoring Junction Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	DNA Binding RNA Binding Structural Molecule Activity Protein Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cell Adhesion RNA Splicing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome DNA-templated Transcription MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRP4K RBM12B RNPS1 SRRM2 SRSF4 USP7 YWHAG ZCCHC17	55 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKTR OGT PICK1 PIN1 PNN PRPF38A PSTPIP1 RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRRM4 SRSF1 SRSF11 SRSF3 SRSF6 SRSF7 SRSF9 STX11 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZSCAN30
Entrez ID		5411	10921
HPRD ID		04401	07341
Ensembl ID		ENSG00000100941	ENSG00000205937
Uniprot IDs		Q9H307	D3DU92 H3BMS0 Q15287
PDB IDs			4A8X
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Keratin Filament RNA Binding Nuclear Speck Intermediate Filament RNA Splicing RNA Splicing, Via Transesterification Reactions White Fat Cell Differentiation Hepatocyte Apoptotic Process Cell Periphery Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Viral Genome Replication Apicolateral Plasma Membrane Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Nuclear Matrix Negative Regulation Of RNA Splicing NAD Binding Cyclic Nucleotide-activated Monoatomic Ion Channel Activity Olfactory Nerve Maturation Nucleoplasm Negative Regulation Of Translational Initiation Nucleus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transcription Coregulator Binding Transcription Corepressor Binding Epithelial Cell Apoptotic Process Structural Molecule Activity MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Non-motile Cilium Membrane Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Negative Regulation Of Proteasomal Protein Catabolic Process Transcription Repressor Complex Tumor Necrosis Factor-mediated Signaling Pathway Structural Constituent Of Skin Epidermis RNA Processing TORC1 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Alternative MRNA Splicing, Via Spliceosome Nerve Maturation Response To Odorant Protein Kinase CK2 Complex Regulation Of Chromosome Separation Regulation Of Intracellular Transport	MRNA Processing RNA Splicing Regulation Of RNA Splicing Nuclear Speck MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nucleus Regulation Of MRNA Processing RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Binding RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleic Acid Binding Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process MRNA Splice Site Recognition Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Positive Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Exon-exon Junction Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly Identical Protein Binding Protein Domain Specific Binding Negative Regulation Of MRNA Metabolic Process Pre-mRNA Binding MRNA Transport ASAP Complex RNA Transport Phosphoserine Residue Binding RS Domain Binding Protein Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Nucleobase-containing Compound Transport Cajal Body
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