RNPS1 and ZNF490

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		RNPS1	ZNF490
Description		RNA binding protein with serine rich domain 1	zinc finger protein 490
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleus
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome DNA-templated Transcription MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Generic Transcription Pathway
Drugs
Diseases
GWAS			Adult body size ( 32376654)
Interacting Genes		55 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKTR OGT PICK1 PIN1 PNN PRPF38A PSTPIP1 RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRRM4 SRSF1 SRSF11 SRSF3 SRSF6 SRSF7 SRSF9 STX11 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZSCAN30	35 interacting genes: CCDC136 CCNDBP1 CEP70 DTNBP1 FSD2 GLRX3 GOLGA6L9 HAP1 HOXB13 KRT40 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 LMNA LZTR1 LZTS2 MDFI MEOX2 MTUS2 NDEL1 RBMX RNPS1 STX1A TBX21 TEX19 TRAF1 TRIM41 TSGA10 VWC2 ZBTB32 ZC4H2 ZRANB1
Entrez ID		10921	57474
HPRD ID		07341	15802
Ensembl ID		ENSG00000205937	ENSG00000188033
Uniprot IDs		D3DU92 H3BMS0 Q15287	Q9ULM2
PDB IDs		4A8X
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing Regulation Of RNA Splicing Nuclear Speck MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nucleus Regulation Of MRNA Processing RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Binding RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleic Acid Binding Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process MRNA Splice Site Recognition Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Positive Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Exon-exon Junction Complex Negative Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly Identical Protein Binding Protein Domain Specific Binding Negative Regulation Of MRNA Metabolic Process Pre-mRNA Binding MRNA Transport ASAP Complex RNA Transport Phosphoserine Residue Binding RS Domain Binding Protein Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Nucleobase-containing Compound Transport Cajal Body	Intermediate Filament Keratin Filament Identical Protein Binding Vesicle Transport Along Microtubule Vesicle Cytoskeletal Trafficking
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