PNN and ZCCHC17

Number of citations of the paper that reports this interaction (PubMedID 12893261)
0

Data Source:
HPRD (two hybrid)

		PNN	ZCCHC17
Description		pinin, desmosome associated protein	zinc finger CCHC-type containing 17
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Anchoring Junction Catalytic Step 2 Spliceosome	Nucleus Nucleolus Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding Structural Molecule Activity Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cell Adhesion RNA Splicing	RNA Stabilization
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Alcohol dependence ( 23455491) Body mass index ( 26426971 29615537)
Interacting Genes		19 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRP4K RBM12B RNPS1 SRRM2 SRSF4 USP7 YWHAG ZCCHC17	16 interacting genes: AP1M1 APP CACNA1A EHHADH KDM1A LXN NTAQ1 PNN RNF4 SDCBP SDCBP2 SHTN1 SRPK2 SUV39H1 ZDHHC17 ZNF16
Entrez ID		5411	51538
HPRD ID		04401	15189
Ensembl ID		ENSG00000100941	ENSG00000121766
Uniprot IDs		Q9H307	A0A087WXF8 A0A087WXU5 A0A087WYF0 A0A087WYV3 A0A0D9SEW3 B4DYA9 Q9NP64
PDB IDs			2CQO
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Keratin Filament RNA Binding Nuclear Speck Intermediate Filament RNA Splicing RNA Splicing, Via Transesterification Reactions White Fat Cell Differentiation Hepatocyte Apoptotic Process Cell Periphery Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Viral Genome Replication Apicolateral Plasma Membrane Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Nuclear Matrix Negative Regulation Of RNA Splicing NAD Binding Cyclic Nucleotide-activated Monoatomic Ion Channel Activity Olfactory Nerve Maturation Nucleoplasm Negative Regulation Of Translational Initiation Nucleus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transcription Coregulator Binding Transcription Corepressor Binding Epithelial Cell Apoptotic Process Structural Molecule Activity MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Non-motile Cilium Membrane Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Negative Regulation Of Proteasomal Protein Catabolic Process Transcription Repressor Complex Tumor Necrosis Factor-mediated Signaling Pathway Structural Constituent Of Skin Epidermis RNA Processing TORC1 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Alternative MRNA Splicing, Via Spliceosome Nerve Maturation Response To Odorant Protein Kinase CK2 Complex Regulation Of Chromosome Separation Regulation Of Intracellular Transport	Substrate-dependent Cell Migration, Cell Extension
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