PNN and CNGB1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PNN	CNGB1
Description		pinin, desmosome associated protein	cyclic nucleotide gated channel subunit beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Anchoring Junction Catalytic Step 2 Spliceosome	Photoreceptor Outer Segment Plasma Membrane Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Golgi-associated Vesicle Membrane Cell Projection Terminal Bouton Ciliary Membrane Non-motile Cilium Membrane Rod Photoreceptor Outer Segment Transmembrane Transporter Complex
	Molecular Function	DNA Binding RNA Binding Structural Molecule Activity Protein Binding	Nucleotide Binding Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Intracellularly CAMP-activated Cation Channel Activity Intracellularly CGMP-activated Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Protein Binding Ligand-gated Monoatomic Ion Channel Activity CAMP Binding CGMP Binding Cyclic Nucleotide-activated Monoatomic Ion Channel Activity Protein-containing Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cell Adhesion RNA Splicing	Retina Homeostasis Monoatomic Ion Transport Monoatomic Cation Transport Potassium Ion Transport Sodium Ion Transport Calcium Ion Transport G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Sensory Perception Of Smell Positive Regulation Of Gene Expression Olfactory Nerve Maturation Protein Localization To Organelle Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Detection Of Light Stimulus Involved In Visual Perception Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell Regulation Of Cytosolic Calcium Ion Concentration Membrane Depolarization Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Response To Odorant
Pathways		mRNA Splicing - Major Pathway	Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS			Initial alcohol sensitivity ( 30276832) Low density lipoprotein cholesterol levels ( 32154731) Prudent dietary pattern ( 28644415) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Triglyceride levels ( 32154731)
Interacting Genes		19 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRP4K RBM12B RNPS1 SRRM2 SRSF4 USP7 YWHAG ZCCHC17	3 interacting genes: ABCA4 PNN PRPH2
Entrez ID		5411	1258
HPRD ID		04401	07204
Ensembl ID		ENSG00000100941	ENSG00000070729
Uniprot IDs		Q9H307	Q14028
PDB IDs			7RH9 7RHG 7RHH 7RHI 7RHJ 7RHK 7RHL 8DGH 8DGK
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Keratin Filament RNA Binding Nuclear Speck Intermediate Filament RNA Splicing RNA Splicing, Via Transesterification Reactions White Fat Cell Differentiation Hepatocyte Apoptotic Process Cell Periphery Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Viral Genome Replication Apicolateral Plasma Membrane Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Nuclear Matrix Negative Regulation Of RNA Splicing NAD Binding Cyclic Nucleotide-activated Monoatomic Ion Channel Activity Olfactory Nerve Maturation Nucleoplasm Negative Regulation Of Translational Initiation Nucleus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transcription Coregulator Binding Transcription Corepressor Binding Epithelial Cell Apoptotic Process Structural Molecule Activity MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Non-motile Cilium Membrane Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Negative Regulation Of Proteasomal Protein Catabolic Process Transcription Repressor Complex Tumor Necrosis Factor-mediated Signaling Pathway Structural Constituent Of Skin Epidermis RNA Processing TORC1 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Alternative MRNA Splicing, Via Spliceosome Nerve Maturation Response To Odorant Protein Kinase CK2 Complex Regulation Of Chromosome Separation Regulation Of Intracellular Transport	N-retinylidene-phosphatidylethanolamine Flippase Activity Rod Photoreceptor Disc Membrane Flippase Activity Detection Of Light Stimulus Detection Of Abiotic Stimulus Photoreceptor Outer Segment Response To Low Light Intensity Stimulus Retinol Transmembrane Transporter Activity Visual Perception Phosphatidylethanolamine Flippase Activity Sensory Perception Of Light Stimulus Phospholipid Transfer To Membrane Retinol Transport Detection Of Stimulus All-trans Retinal Binding Terpenoid Transport 11-cis Retinal Binding Response To Light Stimulus Retinoid Binding Response To Radiation ATPase-coupled Intramembrane Lipid Transporter Activity Sensory Perception Phototransduction, Visible Light Photoreceptor Cell Outer Segment Organization Response To Light Intensity Phospholipid Transporter Activity Retinal Metabolic Process Photoreceptor Disc Membrane Exon-exon Junction Complex Detection Of Light Stimulus Involved In Visual Perception Detection Of Visible Light Protein Heterooligomerization Desmosome ATPase-coupled Transmembrane Transporter Activity Phospholipid Translocation Photoreceptor Cell Maintenance ABC-type Transporter Activity Phototransduction Lipid Translocation Cell Adhesion Nervous System Process Regulation Of Membrane Lipid Distribution Photoreceptor Inner Segment Aldehyde Metabolic Process Retinoid Metabolic Process Diterpenoid Metabolic Process Retina Development In Camera-type Eye Phospholipid Transport Cell Projection Catalytic Step 2 Spliceosome
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