PNN and DYNC1I2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PNN	DYNC1I2
Gene Name		pinin, desmosome associated protein	dynein, cytoplasmic 1, intermediate chain 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle
	Molecular Function	DNA Binding Structural Molecule Activity Poly(A) RNA Binding	Microtubule Motor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Microtubule-based Movement Metabolic Process Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT8 PNISR PPIG PRPF4B RNPS1 SRRM2 SRSF4 YWHAG ZCCHC17	4 interactors: DCTN1 DYNLRB1 DYNLT3 PNN
Entrez ID		5411	1781
HPRD ID		04401	04512
Ensembl ID		ENSG00000100941	ENSG00000077380
Uniprot IDs		Q9H307	B4DPZ3 B7ZA04 Q13409
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Hepatocyte Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome White Fat Cell Differentiation Negative Regulation Of RNA Splicing MRNA Processing Viral Genome Replication RNA Metabolic Process Cell Differentiation Involved In Embryonic Placenta Development Tumor Necrosis Factor-mediated Signaling Pathway MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Gene Expression Sarcomere Organization Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Negative Regulation Of Cellular Metabolic Process DNA-templated Transcription, Termination RNA Export From Nucleus Myofibril Assembly Apoptotic Signaling Pathway Organelle Organization MRNA 3'-end Processing Regulation Of MRNA Processing Negative Regulation Of Chromosome Organization Cellular Response To Tumor Necrosis Factor Cell Differentiation Regulation Of RNA Splicing Extrinsic Apoptotic Signaling Pathway RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Actomyosin Structure Organization Apoptotic Process Embryonic Placenta Development G2/M Transition Of Mitotic Cell Cycle Nuclear Export MRNA Transport Programmed Cell Death Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Tumor Necrosis Factor Fat Cell Differentiation Cell Death Death
Tagcloud ?		accordingly aforementioned ann arrangement artificial axillary carry categorized dissection drop indication input leaving lymph marker markers necessity network nodal node nodes obviate oestrogen output pr predication prediction probabilistic tumour
Tagcloud (Difference) ?		accordingly aforementioned ann arrangement artificial axillary carry categorized dissection drop indication input leaving lymph marker markers necessity network nodal node nodes obviate oestrogen output pr predication prediction probabilistic tumour
Tagcloud (Intersection) ?