CNTNAP1 and RTN4

Number of citations of the paper that reports this interaction (PMID 14592966)
8

Data Source:
HPRD (in vitro, in vivo)

		CNTNAP1	RTN4
Gene Name		contactin associated protein 1	reticulon 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Paranode Region Of Axon	Intracellular Nuclear Envelope Endoplasmic Reticulum Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Cell Projection Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Localization To Paranode Region Of Axon Cytoskeleton Organization Cell Adhesion Signal Transduction Axon Guidance Axon Cargo Transport Positive Regulation Of Signal Transduction Neuronal Action Potential Propagation Paranodal Junction Assembly Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance	Angiogenesis Apoptotic Process Axonal Fasciculation Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of Cell Growth Regulation Of Cell Migration Negative Regulation Of Axon Extension Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Cardiac Epithelial To Mesenchymal Transition Endoplasmic Reticulum Tubular Network Organization Regulation Of Branching Morphogenesis Of A Nerve
Pathways		Axon guidance Neurofascin interactions L1CAM interactions	Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Obesity (extreme) ( 19553259)
Protein-Protein Interactions		8 interactors: CDC42 FYN NFASC PTPRB RAC1 RHOA RTN4 SRC	34 interactors: ARL6IP1 BAIAP2 BCL2 BCL2L1 CLN8 CNTNAP1 COL4A3BP CRMP1 FXR2 HLA-DPB1 LAMA4 LRCH4 LRPAP1 MBP NAPA NR4A1 PLEKHF2 POT1 PRR13 RAB33A RPS27 RTN3 RTN4IP1 RTN4R SNX1 SNX15 SPG21 SYT16 TERF1 TUBA4A UQCRC1 UQCRC2 WWP1 ZFYVE21
Entrez ID		8506	57142
HPRD ID		03825	07259
Ensembl ID		ENSG00000108797	ENSG00000115310
Uniprot IDs		P78357	Q9NQC3
PDB IDs			2G31 2JV5
Enriched GO Terms of Interacting Partners?		Axon Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Axon Guidance Neuron Development Regulation Of Cell Projection Organization Cell Morphogenesis Cell-cell Junction Organization Neurotrophin TRK Receptor Signaling Pathway Axonogenesis Neurotrophin Signaling Pathway Neuron Differentiation Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation T Cell Costimulation Chemotaxis Locomotion Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Movement Of Cell Or Subcellular Component Brain Development Head Development Generation Of Neurons Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cell Motility Enzyme Linked Receptor Protein Signaling Pathway Blood Coagulation Hemostasis Cell Development Central Nervous System Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cell Morphogenesis Platelet Activation Positive Regulation Of T Cell Activation Cellular Response To Growth Factor Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Body Fluid Levels Regulation Of Phosphatidylinositol 3-kinase Activity Response To Growth Factor Leukocyte Migration Wound Healing	Transport Establishment Of Localization In Cell Membrane Organization Cell Part Morphogenesis Intracellular Transport Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Localization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Mitochondrial Membrane Organization Regulation Of Telomere Maintenance Via Telomerase Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Anoikis Regulation Of Telomerase Activity Neuromuscular Process Controlling Posture Regulation Of Anoikis Regulation Of Telomere Maintenance Immune Response-regulating Signaling Pathway RNA-dependent DNA Replication Regulation Of Autophagy Mitochondrion Morphogenesis Cell Morphogenesis Negative Regulation Of DNA Biosynthetic Process Vesicle-mediated Transport Immune Response-activating Cell Surface Receptor Signaling Pathway System Development Neuron Differentiation Nervous System Development Axonogenesis Release Of Cytochrome C From Mitochondria Regulation Of Cellular Component Organization Cell Projection Morphogenesis Telomere Maintenance Via Telomere Lengthening Antigen Receptor-mediated Signaling Pathway Generation Of Neurons Anatomical Structure Development Aging Axon Development Developmental Process Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Response To Alkaloid Regulation Of Mitochondrial Membrane Permeability Cell Morphogenesis Involved In Neuron Differentiation Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Membrane Permeability Neurogenesis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud ?			advance caspase caspases cdd corrected crosstalk disrupted doi emerges extrinsic flice flip flipl impinging initiator juxtaposition localizes mams mechanistically mefs mitochondria morphology platforms publication restrict reticulon shaping spatially tethering
Tagcloud (Difference) ?			advance caspase caspases cdd corrected crosstalk disrupted doi emerges extrinsic flice flip flipl impinging initiator juxtaposition localizes mams mechanistically mefs mitochondria morphology platforms publication restrict reticulon shaping spatially tethering
Tagcloud (Intersection) ?