ATP6AP1 and LARP1

		ATP6AP1	LARP1
Description		ATPase H+ transporting accessory protein 1	La ribonucleoprotein 1, translational regulator
Image
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Proton-transporting Two-sector ATPase Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase Complex Synapse Extracellular Exosome Bounding Membrane Of Organelle	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane TORC1 Complex
	Molecular Function	ATPase Activator Activity Protein Binding Small GTPase Binding Transporter Activator Activity	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding
	Biological Process	Monoatomic Ion Transport Intracellular Iron Ion Homeostasis Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Cellular PH Osteoclast Development Cellular Response To Increased Oxygen Levels Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Endosome To Plasma Membrane Protein Transport Proton Transmembrane Transport	Translation Translational Initiation Regulation Of Translation Cell Population Proliferation Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation
Pathways		Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport	SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs		Tiludronic acid
Diseases
GWAS			Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		6 interacting genes: ANG ERBB2 HBA1 NR1I2 OGT RHOU	13 interacting genes: BCL2L1 CEBPA CLNS1A CSNK2A1 KASH5 RNF10 SRPK1 TNNT1 UBXN7 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		537	23367
HPRD ID		02184	11225
Ensembl ID		ENSG00000071553	ENSG00000155506
Uniprot IDs		A0A384MQW4 Q15904	A0A8I5KSP1 A0A8I5KWU3 Q6PKG0
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF	4ZC4 5C0V 5V4R 5V7C 5V87 6PW3 7SOO 7SOP 7SOQ 7SOR 7SOS 7SOT 7SOU 7SOV 7SOW 8EY6 8EY7 8EY8 8G90 8G91 8XP2 8XP3
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Catabolic Process Sulfur Compound Transmembrane Transporter Activity Positive Regulation Of Lipid Biosynthetic Process Fatty-acyl-CoA Transport Very Long-chain Fatty-acyl-CoA Metabolic Process Organophosphate Ester Transmembrane Transporter Activity Very Long-chain Fatty-acyl-CoA Catabolic Process Amide Transmembrane Transporter Activity Very Long-chain Fatty Acyl-CoA Hydrolase Activity Nucleobase-containing Compound Transmembrane Transporter Activity Homeostatic Process ABC-type Fatty-acyl-CoA Transporter Activity Catabolic Process Cytosol Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process RNA Stabilization TRNA-specific Ribonuclease Activity Regulation Of Translation Cytoplasmic Stress Granule Membraneless Organelle Assembly Angiogenin-PRI Complex Negative Regulation Of Catabolic Process Regulation Of Protein Localization Translation Positive Regulation Of Establishment Of Protein Localization XPC Complex RNA Polymerase I Core Binding ERBB3:ERBB2 Complex Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Translation Haptoglobin Binding 5'-deoxynucleotidase Activity Adenosine Biosynthetic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translational Initiation TOR Signaling Positive Regulation Of Translational Initiation TORC1 Signaling Protein O-acetylglucosaminyltransferase Activity Cellular Response To Rapamycin Regulation Of Translational Initiation Nucleoside Phosphate Catabolic Process Regulation Of Biological Quality Regulation Of Generation Of Precursor Metabolites And Energy Fatty-acyl-CoA Catabolic Process Long-chain Fatty Acid Import Into Peroxisome Cytoplasmic Translation	Protein Domain Specific Binding Protein Targeting Protein Sequestering Activity Phosphoserine Residue Binding Establishment Of Protein Localization Intracellular Signal Transduction Identical Protein Binding Cytosol Positive Regulation Of Viral Genome Replication
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?