LARP1

Name	La ribonucleoprotein 1, translational regulator
Structure
Novel Interactors	4 novel interactors: ATP6AP1 LCP2 PPID PPL
Interactors	13 interactors: BCL2L1 CEBPA CLNS1A CSNK2A1 KASH5 RNF10 SRPK1 TNNT1 UBXN7 YWHAB YWHAG YWHAQ YWHAZ
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane TORC1 Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Cell Population Proliferation Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation
Pathways	SARS-CoV-2 activates/modulates innate and adaptive immune responses
GWAS	Chin dimples ( 27182965 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Mean corpuscular hemoglobin ( 32888494 ) Mean corpuscular volume ( 32888494 ) Monobrow ( 27182965 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 )
Entrez ID	23367
HPRD ID	11225
Ensembl ID	ENSG00000155506
Uniprot IDs	A0A8I5KSP1 A0A8I5KWU3 Q6PKG0
PDB IDs	4ZC4 5C0V 5V4R 5V7C 5V87 6PW3 7SOO 7SOP 7SOQ 7SOR 7SOS 7SOT 7SOU 7SOV 7SOW 8EY6 8EY7 8EY8 8G90 8G91 8XP2 8XP3
GO Terms Enriched among Interactors ?	Protein Domain Specific Binding Protein Targeting Protein Sequestering Activity Phosphoserine Residue Binding Establishment Of Protein Localization Intracellular Signal Transduction Identical Protein Binding Cytosol Positive Regulation Of Viral Genome Replication