LARP1 and LCP2

		LARP1	LCP2
Description		La ribonucleoprotein 1, translational regulator	lymphocyte cytosolic protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane TORC1 Complex	Cytoplasm Cytosol Cell-cell Junction TCR Signalosome Plasma Membrane Raft
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding	Protein Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Cell Population Proliferation Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation	Immune System Process Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Intracellular Signal Transduction Mast Cell Activation Positive Regulation Of Protein Kinase Activity T Cell Receptor Signaling Pathway
Pathways		SARS-CoV-2 activates/modulates innate and adaptive immune responses	GPVI-mediated activation cascade Generation of second messenger molecules Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization
Drugs
Diseases
GWAS		Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Acne (severe) ( 24927181) Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		13 interacting genes: BCL2L1 CEBPA CLNS1A CSNK2A1 KASH5 RNF10 SRPK1 TNNT1 UBXN7 YWHAB YWHAG YWHAQ YWHAZ	48 interacting genes: APP BLNK CBL CD22 CLNK EGFR ELOVL6 ERBB2 ERBB3 ERBB4 FXR2 FYB1 FYN GOLGA2 GRAP2 GRB2 HCK ITK LAT LCK LMNA LNX1 LYN MAP4K1 NCK1 NCK2 PAG1 PJA1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SH3RF1 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAE YWHAZ ZAP70
Entrez ID		23367	3937
HPRD ID		11225	03362
Ensembl ID		ENSG00000155506	ENSG00000043462
Uniprot IDs		A0A8I5KSP1 A0A8I5KWU3 Q6PKG0	Q13094
PDB IDs		4ZC4 5C0V 5V4R 5V7C 5V87 6PW3 7SOO 7SOP 7SOQ 7SOR 7SOS 7SOT 7SOU 7SOV 7SOW 8EY6 8EY7 8EY8 8G90 8G91 8XP2 8XP3	1H3H 1YWO 2EAP 2ROR 6ZCJ
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Protein Targeting Protein Sequestering Activity Phosphoserine Residue Binding Establishment Of Protein Localization Intracellular Signal Transduction Identical Protein Binding Cytosol Positive Regulation Of Viral Genome Replication	Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Signaling Pathway Phosphotyrosine Residue Binding Immune Response-regulating Signaling Pathway Activation Of Immune Response Regulation Of Immune Response Regulation Of Immune System Process Positive Regulation Of Immune Response T Cell Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune System Process Cell Surface Receptor Signaling Pathway Lymphocyte Activation Intracellular Signal Transduction Leukocyte Activation Signal Transduction Cell Activation Regulation Of MAPK Cascade Regulation Of Lymphocyte Activation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Intracellular Signal Transduction Protein Tyrosine Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of T Cell Activation Peptidyl-tyrosine Phosphorylation Fc Receptor Signaling Pathway Intracellular Signaling Cassette T Cell Activation Positive Regulation Of MAPK Cascade Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Multicellular Organismal Process Non-membrane Spanning Protein Tyrosine Kinase Activity Membrane Raft Ephrin Receptor Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Signal Transduction Positive Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Positive Regulation Of T Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Lymphocyte Activation Negative Regulation Of Immune System Process Regulation Of Signaling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?