PLK1 and FZR1

  • Number of citations of the paper that reports this interaction (PMID 23972993)
  • 3
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

PLK1

FZR1

Gene Name polo-like kinase 1 fizzy/cell division cycle 20 related 1 (Drosophila)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 99 interactors: ACTL6B APP ASPM BAG6 BIRC6 BRCA2 BUB1 C6orf136 C9orf114 CCDC115 CCNB1 CDC20 CDC25C CENPQ CENPU CEP55 CHEK2 CIC CPSF3L CSN1S1 CSN2 CTNNB1 DNAJB9 DNHD1 ECT2 EIF6 FBXL5 FLJ20712 FZR1 GET4 GLB1 GORASP1 HSF1 IKBKB ITSN1 KIF23 KLHL22 KRBA1 LMO4 LRP5L MAGED1 MAPK6 MCM2 MCM3 MCM7 MDM2 MPP2 MYT1 NEDD4 NINL NPM1 NUDC OFD1 PHC2 PIN1 PITPNM1 PKMYT1 PPID PRC1 PSMA1 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 RABAC1 RAP1GAP RBX1 RECQL5 RELA RNF126 RXRA SIMC1 SNCA SNCB STAG2 SUGT1 TANK TNFSF11 TP53 TP53BP1 TP53BP2 TPT1 TRIOBP TSC1 TUBA4A TUBB TUBB3 TUBG1 VRK3 WEE1 ZNF71 42 interactors: ANAPC1 ANAPC2 ANAPC4 ANAPC5 ANAPC7 BUB1B C7orf25 CCNA2 CCNB1 CDC14A CDC20 CDC25A CDC27 CDC6 CDK1 CDK2 CDR2 CDT1 CLSPN DNAJA1 E2F3 FBXO5 HECW2 MAK MAPK8 MOAP1 PLK1 PTEN PTTG1 RBBP8 SIRT2 SKIL SKP2 SOX2 TK1 TP53 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2S
Entrez ID 5347 51343
HPRD ID 03652 04687
Ensembl ID ENSG00000166851
Uniprot IDs P53350 Q9UM11
PDB IDs 1Q4K 1Q4O 1UMW 2OGQ 2OJX 2OU7 2OWB 2RKU 2V5Q 2YAC 3BZI 3C5L 3FC2 3FVH 3HIH 3HIK 3KB7 3P2W 3P2Z 3P34 3P35 3P36 3P37 3Q1I 3RQ7 3THB 4A4L 4A4O 4DFW 4E67 4E9C 4E9D 4H5X 4H71 4HAB 4HCO 4HY2 4J52 4J53
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  atm  brca1  cdk1  comparatively  coordinates  cytosol  ddr  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  localize  mitosis  mitotic  properly  recombination  rnf168  rnf8  s1618  spatiotemporally  ubiquitinated 
anaphase  cdc20  cdh1  chromosomes  clathrin  clta  cltc  concentrated  diffusely  g2  gst  interactor  kinetochore  localize  mad2b  mad2l2  misaligned  mitotic  p11  prcc  pull  q21  rccs  redistribution  shuttle  spindle  tfe3  trimeric  triskelion 
Tagcloud (Difference) ?
53bp1  atm  brca1  cdk1  comparatively  coordinates  cytosol  ddr  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  mitosis  properly  recombination  rnf168  rnf8  s1618  spatiotemporally  ubiquitinated 
anaphase  cdc20  cdh1  chromosomes  clathrin  clta  cltc  concentrated  diffusely  g2  gst  interactor  kinetochore  mad2b  mad2l2  misaligned  p11  prcc  pull  q21  rccs  redistribution  shuttle  spindle  tfe3  trimeric  triskelion 
Tagcloud (Intersection) ?
localize  mitotic