PLK1 and ASPM

  • Number of citations of the paper that reports this interaction (PMID 11283617)
  • 25
  • Data Source:
  • HPRD (in vitro)

PLK1

ASPM

Gene Name polo-like kinase 1 asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 23536807)
Protein-Protein Interactions 99 interactors: ACTL6B APP ASPM BAG6 BIRC6 BRCA2 BUB1 C6orf136 C9orf114 CCDC115 CCNB1 CDC20 CDC25C CENPQ CENPU CEP55 CHEK2 CIC CPSF3L CSN1S1 CSN2 CTNNB1 DNAJB9 DNHD1 ECT2 EIF6 FBXL5 FLJ20712 FZR1 GET4 GLB1 GORASP1 HSF1 IKBKB ITSN1 KIF23 KLHL22 KRBA1 LMO4 LRP5L MAGED1 MAPK6 MCM2 MCM3 MCM7 MDM2 MPP2 MYT1 NEDD4 NINL NPM1 NUDC OFD1 PHC2 PIN1 PITPNM1 PKMYT1 PPID PRC1 PSMA1 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 RABAC1 RAP1GAP RBX1 RECQL5 RELA RNF126 RXRA SIMC1 SNCA SNCB STAG2 SUGT1 TANK TNFSF11 TP53 TP53BP1 TP53BP2 TPT1 TRIOBP TSC1 TUBA4A TUBB TUBB3 TUBG1 VRK3 WEE1 ZNF71 2 interactors: LIG4 PLK1
Entrez ID 5347 259266
HPRD ID 03652 08384
Ensembl ID ENSG00000166851 ENSG00000066279
Uniprot IDs P53350 B3KWI2 Q8IZT6
PDB IDs 1Q4K 1Q4O 1UMW 2OGQ 2OJX 2OU7 2OWB 2RKU 2V5Q 2YAC 3BZI 3C5L 3FC2 3FVH 3HIH 3HIK 3KB7 3P2W 3P2Z 3P34 3P35 3P36 3P37 3Q1I 3RQ7 3THB 4A4L 4A4O 4DFW 4E67 4E9C 4E9D 4H5X 4H71 4HAB 4HCO 4HY2 4J52 4J53
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  atm  brca1  cdk1  comparatively  coordinates  cytosol  ddr  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  localize  mitosis  mitotic  properly  recombination  rnf168  rnf8  s1618  spatiotemporally  ubiquitinated 
0x  1x  adamts13  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  ppp1ca  prkdc  resequencing  rnf168  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
Tagcloud (Difference) ?
53bp1  atm  brca1  cdk1  comparatively  coordinates  cytosol  ddr  enables  exit  flanking  genotoxic  h2a  homologous  impairs  interphase  joining  kinetochores  ligases  localize  mitosis  mitotic  properly  recombination  rnf8  s1618  spatiotemporally  ubiquitinated 
0x  1x  adamts13  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  ppp1ca  prkdc  resequencing  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
Tagcloud (Intersection) ?
rnf168