PLCD1 and RALB

Number of citations of the paper that reports this interaction (PMID 15817490)
13

Data Source:
HPRD (two hybrid, in vitro)

		PLCD1	RALB
Gene Name		phospholipase C, delta 1	v-ral simian leukemia viral oncogene homolog B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome	Exocyst Autophagic Vacuole Plasma Membrane Midbody Extracellular Vesicular Exosome
	Molecular Function	Phosphatidylserine Binding Phosphatidylinositol Phospholipase C Activity Signal Transducer Activity Calcium Ion Binding GTPase Activating Protein Binding Phosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding
	Biological Process	Angiogenesis Phospholipid Metabolic Process Lipid Catabolic Process Intracellular Signal Transduction Regulation Of Cell Proliferation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Labyrinthine Layer Blood Vessel Development	Cytokinesis Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagic Vacuole Assembly
Pathways		Synthesis of IP3 and IP4 in the cytosol Inositol phosphate metabolism	Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP CALM1 GAP43 KPNB1 PAXIP1 RALA RALB TGM2	6 interactors: CALM1 PLCD1 RALBP1 REPS1 REPS2 RGL4
Entrez ID		5333	5899
HPRD ID		09073	01550
Ensembl ID		ENSG00000187091	ENSG00000144118
Uniprot IDs		A8K8F9 P51178	B4E040 P11234 Q6ZS74
PDB IDs			2KE5 2KWI
Enriched GO Terms of Interacting Partners?		Axon Choice Point Recognition Cell Surface Receptor Signaling Pathway Signal Transduction Signaling Cell Communication Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition Regulation Of Filopodium Assembly Positive Regulation Of Cellular Component Biogenesis Response To External Stimulus Exocytosis Response To Stimulus Regulation Of Cellular Amino Acid Metabolic Process Platelet Degranulation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Regulation Of Exocyst Assembly Response To Radiation Positive Regulation Of Protein Metabolic Process Locomotion Regulation Of Cellular Ketone Metabolic Process Secretion By Cell Cytokinesis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Synaptic Growth At Neuromuscular Junction Positive Regulation Of Autophagic Vacuole Assembly Regulation Of Exocyst Localization Positive Regulation Of Vacuole Organization Regulation Of Cell Projection Assembly Cellular Response To Growth Factor Stimulus Cell Recognition Vesicle-mediated Transport Wound Healing Chemotaxis Response To Growth Factor Secretion Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Exocytosis Response To Wounding Membrane Raft Localization Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Protein Kinase Activity Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity	Inositol Phosphate Metabolic Process Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Hydrolase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Signal Transduction Detection Of Calcium Ion Alcohol Metabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Signaling Cell Communication Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cdc42 GTPase Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Labyrinthine Layer Blood Vessel Development Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Autophosphorylation Cellular Response To Stimulus Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine
Tagcloud ?		adapt beside bloodstream codify depend differently differs ec endothelium enzymes evidences excepting finely neuroendocrine neuropeptide npy phosphoinositide phospholipase pi plcb2 plce potentiate quiescent react transduction tuned umbilical upcoming	adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Difference) ?		adapt beside bloodstream codify depend differently differs ec endothelium enzymes evidences excepting finely neuroendocrine neuropeptide npy phosphoinositide phospholipase pi plcb2 plce potentiate quiescent react transduction tuned umbilical upcoming	adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Intersection) ?