PLCD1 and GAP43

Number of citations of the paper that reports this interaction (PMID 12805215)
3

Data Source:
HPRD (in vivo)

		PLCD1	GAP43
Gene Name		phospholipase C, delta 1	growth associated protein 43
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane Postsynaptic Density Cell Junction Axon Filopodium Membrane Growth Cone Membrane
	Molecular Function	Phosphatidylserine Binding Phosphatidylinositol Phospholipase C Activity Signal Transducer Activity Calcium Ion Binding GTPase Activating Protein Binding Phosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	Protein Binding Calmodulin Binding
	Biological Process	Angiogenesis Phospholipid Metabolic Process Lipid Catabolic Process Intracellular Signal Transduction Regulation Of Cell Proliferation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Labyrinthine Layer Blood Vessel Development	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Axon Development
Pathways		Synthesis of IP3 and IP4 in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS			Breast size ( 22747683)
Protein-Protein Interactions		8 interactors: APP CALM1 GAP43 KPNB1 PAXIP1 RALA RALB TGM2	8 interactors: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1
Entrez ID		5333	2596
HPRD ID		09073	01198
Ensembl ID		ENSG00000187091	ENSG00000172020
Uniprot IDs		A8K8F9 P51178	P17677 Q5U058
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Choice Point Recognition Cell Surface Receptor Signaling Pathway Signal Transduction Signaling Cell Communication Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition Regulation Of Filopodium Assembly Positive Regulation Of Cellular Component Biogenesis Response To External Stimulus Exocytosis Response To Stimulus Regulation Of Cellular Amino Acid Metabolic Process Platelet Degranulation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Regulation Of Exocyst Assembly Response To Radiation Positive Regulation Of Protein Metabolic Process Locomotion Regulation Of Cellular Ketone Metabolic Process Secretion By Cell Cytokinesis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Synaptic Growth At Neuromuscular Junction Positive Regulation Of Autophagic Vacuole Assembly Regulation Of Exocyst Localization Positive Regulation Of Vacuole Organization Regulation Of Cell Projection Assembly Cellular Response To Growth Factor Stimulus Cell Recognition Vesicle-mediated Transport Wound Healing Chemotaxis Response To Growth Factor Secretion Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Exocytosis Response To Wounding Membrane Raft Localization Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Protein Kinase Activity Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity	Vascular Endothelial Growth Factor Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Dephosphorylation Platelet Activation Negative Regulation Of Insulin Receptor Signaling Pathway Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Blood Coagulation Hemostasis Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Negative Regulation Of Protein Polymerization Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Immune Response-regulating Signaling Pathway Positive Regulation Of Phospholipid Catabolic Process Histone H3-T6 Phosphorylation Regulation Of Body Fluid Levels Regulation Of Dephosphorylation Wound Healing Negative Regulation Of Protein Complex Assembly Interleukin-10 Production Phosphate-containing Compound Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Activation Cell Activation Response To Wounding Negative Regulation Of Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Filopodium Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Actin Filament Polymerization Interleukin-12 Production
Tagcloud ?		adapt beside bloodstream codify depend differently differs ec endothelium enzymes evidences excepting finely neuroendocrine neuropeptide npy phosphoinositide phospholipase pi plcb2 plce potentiate quiescent react transduction tuned umbilical upcoming
Tagcloud (Difference) ?		adapt beside bloodstream codify depend differently differs ec endothelium enzymes evidences excepting finely neuroendocrine neuropeptide npy phosphoinositide phospholipase pi plcb2 plce potentiate quiescent react transduction tuned umbilical upcoming
Tagcloud (Intersection) ?