ATP6V0B and RPS26P15

Data Source: HiPPIP (Novel)

		ATP6V0B	RPS26P15
Name		ATPase H+ transporting V0 subunit b	ribosomal protein S26 pseudogene 15
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Proton-transporting V-type ATPase, V0 Domain	None
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	None
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	None
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	None
Drugs		Tiludronic acid	None
GWAS		Autism spectrum disorder or schizophrenia ( 28540026 )	No GWAS studies recorded
Novel Interactors		6 novel interactors: BPI CCL19 DAPK2 RPS26P15 TTC39A ZFYVE9	2 novel interactors: ATP6V0B NRDC
Interacting Genes		28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG	None recorded
Entrez ID		533	644928
HPRD ID		04759	19237
Ensembl ID		ENSG00000117410	Not available
Uniprot IDs		E9PNL3 Q99437	Not available
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF	Not available
GO Terms Enriched among Interactors		Membrane Specific Granule Membrane Gap Junction-mediated Intercellular Transport Protein Sequestering Activity Intercellular Transport	Endosomal Lumen Acidification Proton-transporting V-type ATPase, V0 Domain Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Golgi Lumen Acidification Proton-transporting V-type ATPase Complex Vacuolar Proton-transporting V-type ATPase, V0 Domain Positive Regulation Of Membrane Protein Ectodomain Proteolysis Endopeptidase Activator Activity Epidermal Growth Factor Binding Positive Regulation Of Myelination Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Lysosomal Lumen Acidification Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Membrane Protein Ectodomain Proteolysis Clathrin-coated Vesicle Membrane Regulation Of Lysosomal Lumen PH Vacuolar Acidification Regulation Of Myelination Negative Regulation Of Cold-induced Thermogenesis Intracellular PH Reduction Positive Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Positive Regulation Of Axonogenesis Phagocytic Vesicle Membrane