ATP6V0B

Gene Name		ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Transporter Activity Hydrogen Ion Transmembrane Transporter Activity
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: FAS IRAK3 SNTA1 YWHAG
Entrez ID		533
HPRD ID		04759
Ensembl ID		ENSG00000117410
Uniprot IDs		E9PNL3 Q99437
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Macrophage Tolerance Induction Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Metabolic Process Motor Neuron Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Peptidyl-cysteine S-nitrosylation Necroptotic Signaling Pathway Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Transformed Cell Apoptotic Process Activation-induced Cell Death Of T Cells Apoptotic Signaling Pathway Inflammatory Cell Apoptotic Process Negative Regulation Of Immune System Process Cellular Response To Hyperoxia Positive Regulation Of Protein Homooligomerization Negative Regulation Of Phosphorylation Cellular Response To Organic Substance Pantothenate Metabolic Process Regulation Of Cellular Component Organization Response To Peptidoglycan Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Negative Thymic T Cell Selection Negative T Cell Selection Long-chain Fatty-acyl-CoA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Lithium Ion T Cell Apoptotic Process Interleukin-1-mediated Signaling Pathway Fatty-acyl-CoA Biosynthetic Process Positive Regulation Of Protein Oligomerization Hepatocyte Apoptotic Process Ventricular Cardiac Muscle Cell Action Potential Cellular Response To Cytokine Stimulus Positive Regulation Of Apoptotic Process Negative Regulation Of Interleukin-12 Production Positive Regulation Of Programmed Cell Death Regulation Of Membrane Repolarization Thymic T Cell Selection Acetyl-CoA Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Long-chain Fatty-acyl-CoA Metabolic Process Regulation Of Catalytic Activity
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