ATP6V0B

Name	ATPase H+ transporting V0 subunit b
Structure
Novel Interactors	6 novel interactors: BPI CCL19 DAPK2 RPS26P15 TTC39A ZFYVE9
Interactors	28 interactors: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport
Pathways	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs	Tiludronic acid
GWAS	Autism spectrum disorder or schizophrenia ( 28540026 )
Entrez ID	533
HPRD ID	04759
Ensembl ID	ENSG00000117410
Uniprot IDs	E9PNL3 Q99437
PDB IDs	6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
GO Terms Enriched among Interactors ?	Membrane Specific Granule Membrane Gap Junction-mediated Intercellular Transport Protein Sequestering Activity Intercellular Transport