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PKP2 and KRT18
Number of citations of the paper that reports this interaction (PubMedID
10852826
)
0
Data Source:
HPRD
(in vitro)
PKP2
KRT18
Description
plakophilin 2
keratin 18
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Nucleoplasm
Cytoplasm
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Intercalated Disc
Membrane
Cell Junction
Desmosome
Cell Tip
Anchoring Junction
Nucleus
Nucleolus
Cytoplasm
Microtubule Organizing Center
Cytosol
Cytoskeleton
Intermediate Filament
Adherens Junction
Nuclear Matrix
Centriolar Satellite
Keratin Filament
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Molecular Function
DNA Binding
Protein Kinase C Binding
Protein Binding
Sodium Channel Regulator Activity
Intermediate Filament Binding
Transmembrane Transporter Binding
Alpha-catenin Binding
Cadherin Binding
Molecular Adaptor Activity
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
RNA Binding
Structural Molecule Activity
Protein Binding
Scaffold Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
Biological Process
Desmosome Assembly
Desmosome Organization
Cell Adhesion
Cell-cell Signaling
Heart Development
Positive Regulation Of Sodium Ion Transport
Regulation Of Cell-substrate Adhesion
Intermediate Filament Bundle Assembly
Maintenance Of Animal Organ Identity
Ventricular Cardiac Muscle Tissue Morphogenesis
Protein Localization To Plasma Membrane
Cardiac Muscle Cell Action Potential Involved In Contraction
Ventricular Cardiac Muscle Cell Action Potential
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Maintenance Of Protein Localization At Cell Tip
Regulation Of Substrate Adhesion-dependent Cell Spreading
Anatomical Structure Morphogenesis
Tumor Necrosis Factor-mediated Signaling Pathway
Golgi To Plasma Membrane Protein Transport
Negative Regulation Of Apoptotic Process
Intermediate Filament Cytoskeleton Organization
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Cell-cell Adhesion
Pathways
Keratinization
Formation of the cornified envelope
Keratinization
Formation of the cornified envelope
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS
Atrial fibrillation (
29892015
30061737
)
Blood protein levels (
30072576
)
Body mass index (change over time) in lung cancer (
28044437
)
Methadone dose in opioid dependence (
28115739
)
Obesity-related traits (
23251661
)
Parkinson's disease (
27182965
32201043
)
Periodontal disease related phenotype (PCT5) (
26962152
)
Prevalent atrial fibrillation (
28416818
)
Diffusing capacity of carbon monoxide (
30694715
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Interacting Genes
48 interacting genes:
ACTN3
AKAP9
ARMC8
BAG4
CARD9
CASK
CCDC120
CCDC125
CCHCR1
CTBP1
CTNNB1
DMRTB1
DSC1
DSC2
DSG1
DSG2
DSP
EIF4ENIF1
EXOSC8
FHL3
GOLGA2
GRIPAP1
GTF2IRD1
HOOK2
HSPB2
JUP
KLC4
KRT18
KRT31
KRT5
MAGOHB
MARK3
MTUS2
NCKIPSD
NDEL1
PIBF1
PLEKHG4
POLR3A
RABEP1
RBM5
RBPMS
ROPN1
SMAD9
SPTA1
TEKT4
VHL
VIM
YWHAG
94 interacting genes:
AIRIM
BBS1
BBS2
BBS4
BBS7
CAMK2A
CASP3
CASP6
CASP7
CASP8
CBL
CCDC146
CCDC85B
CCHCR1
CCNI
CDC5L
CDK1
COL17A1
DEDD
DNAJB6
EFHC1
EGFR
EP300
ESR1
EXOC8
FRAT1
FXR1
FXR2
GIT2
GOLGA2
GRN
HAUS1
HGS
HRAS
HSPA1A
HSPA4
HSPA5
HSPB1
IKBKG
KIFC3
KPNA2
KRT15
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT8
KRT81
LDOC1
LINC01554
MAPK14
NEFL
NME7
ORC5
PDE4B
PDE4DIP
PIAS4
PKD1
PKP2
PKP3
PNN
POT1
PRKCA
PRKCE
PSTPIP2
RAF1
RCOR3
RHPN2
RPS6KA3
SERPINE1
SHC1
SMARCD1
SVIL
SYCE1
TCHP
TEKT4
TNFRSF1B
TRADD
TSG101
TUBG1
TUBGCP4
TXN2
TXNDC11
UPF2
USH2A
WBP2
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAZ
Entrez ID
5318
3875
HPRD ID
04177
01020
Ensembl ID
ENSG00000057294
ENSG00000111057
Uniprot IDs
A0A8V8TPU9
A0AAQ5BGY2
Q99959
P05783
PDB IDs
3TT9
Enriched GO Terms of Interacting Partners
?
Desmosome
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Cardiac Muscle Cell-cardiac Muscle Cell Adhesion
Cytoskeleton Organization
Cornified Envelope
Regulation Of Cardiac Muscle Cell Action Potential
Cytoplasm
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Desmosome Organization
Regulation Of Heart Rate By Cardiac Conduction
Intercalated Disc
Cardiac Conduction
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament
Cytoskeleton
Regulation Of Action Potential
Cytosol
Regulation Of Cardiac Muscle Cell Contraction
Cell Junction
Scaffold Protein Binding
Heterotypic Cell-cell Adhesion
Microtubule Organizing Center
Regulation Of Striated Muscle Contraction
Structural Constituent Of Cytoskeleton
Regulation Of Heart Rate
Cell-cell Junction Organization
Organelle Organization
Catenin-TCF7L2 Complex
Cell-cell Junction
Homotypic Cell-cell Adhesion
Intracellular Protein Localization
Protein Binding
Intermediate Filament Organization
Cellular Response To Indole-3-methanol
Regulation Of Muscle System Process
Nucleus
Regulation Of Cardiac Muscle Contraction
Microtubule Nucleation
Cell-cell Adhesion
Microtubule-based Process
Response To Indole-3-methanol
Regulation Of Muscle Contraction
Anchoring Junction
Fascia Adherens
Adherens Junction
Focal Adhesion
Protein-DNA Complex
Regulation Of Heart Contraction
Cytosol
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Intermediate Filament Organization
Cytoplasm
Organelle Organization
Cytoskeleton Organization
Intermediate Filament
Keratin Filament
Structural Constituent Of Skin Epidermis
Cytoskeleton
Establishment Of Protein Localization
Nucleus
Developmental Process
Supramolecular Fiber Organization
BBSome
Regulation Of Apoptotic Process
Intracellular Protein Localization
Protein Domain Specific Binding
Regulation Of Programmed Cell Death
Cellular Component Assembly
Centrosome
Regulation Of Protein Metabolic Process
Keratinization
Establishment Of Localization In Cell
Reproductive Process
Response To Lipid
Enzyme Binding
Apoptotic Process
Protein Binding
Regulation Of Cellular Component Organization
Programmed Cell Death
Cell Death
Cellular Response To Staurosporine
Ciliary Basal Body
Cellular Localization
Negative Regulation Of Programmed Cell Death
Apoptotic Signaling Pathway
Regulation Of Protein Localization
Intracellular Signal Transduction
Hippocampus Development
Regulation Of Microtubule Nucleation
Phosphoserine Residue Binding
Focal Adhesion
Pyroptotic Inflammatory Response
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Apoptotic Process
Regulation Of Macromolecule Biosynthetic Process
Death-inducing Signaling Complex
Desmosome Assembly
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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