KRT18 and PNN

Number of citations of the paper that reports this interaction (PubMedID 10809736)
0

Data Source:
HPRD (two hybrid, in vitro)

		KRT18	PNN
Description		keratin 18	pinin, desmosome associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Intermediate Filament Adherens Junction Nuclear Matrix Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Nucleus Nucleoplasm Spliceosomal Complex Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Anchoring Junction Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	DNA Binding RNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Anatomical Structure Morphogenesis Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Cell-cell Adhesion	MRNA Splicing, Via Spliceosome MRNA Processing Cell Adhesion RNA Splicing
Pathways		Keratinization Formation of the cornified envelope Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715) Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		94 interacting genes: AIRIM BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCHCR1 CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EFHC1 EGFR EP300 ESR1 EXOC8 FRAT1 FXR1 FXR2 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 HSPB1 IKBKG KIFC3 KPNA2 KRT15 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LDOC1 LINC01554 MAPK14 NEFL NME7 ORC5 PDE4B PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE PSTPIP2 RAF1 RCOR3 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SVIL SYCE1 TCHP TEKT4 TNFRSF1B TRADD TSG101 TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A WBP2 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	19 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRP4K RBM12B RNPS1 SRRM2 SRSF4 USP7 YWHAG ZCCHC17
Entrez ID		3875	5411
HPRD ID		01020	04401
Ensembl ID		ENSG00000111057	ENSG00000100941
Uniprot IDs		P05783	Q9H307
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Cytoplasm Organelle Organization Cytoskeleton Organization Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Cytoskeleton Establishment Of Protein Localization Nucleus Developmental Process Supramolecular Fiber Organization BBSome Regulation Of Apoptotic Process Intracellular Protein Localization Protein Domain Specific Binding Regulation Of Programmed Cell Death Cellular Component Assembly Centrosome Regulation Of Protein Metabolic Process Keratinization Establishment Of Localization In Cell Reproductive Process Response To Lipid Enzyme Binding Apoptotic Process Protein Binding Regulation Of Cellular Component Organization Programmed Cell Death Cell Death Cellular Response To Staurosporine Ciliary Basal Body Cellular Localization Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Hippocampus Development Regulation Of Microtubule Nucleation Phosphoserine Residue Binding Focal Adhesion Pyroptotic Inflammatory Response Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of Macromolecule Biosynthetic Process Death-inducing Signaling Complex Desmosome Assembly	Symbiont-mediated Disruption Of Host Cell PML Body Keratin Filament RNA Binding Nuclear Speck Intermediate Filament RNA Splicing RNA Splicing, Via Transesterification Reactions White Fat Cell Differentiation Hepatocyte Apoptotic Process Cell Periphery Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Viral Genome Replication Apicolateral Plasma Membrane Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Nuclear Matrix Negative Regulation Of RNA Splicing NAD Binding Cyclic Nucleotide-activated Monoatomic Ion Channel Activity Olfactory Nerve Maturation Nucleoplasm Negative Regulation Of Translational Initiation Nucleus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transcription Coregulator Binding Transcription Corepressor Binding Epithelial Cell Apoptotic Process Structural Molecule Activity MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Non-motile Cilium Membrane Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Negative Regulation Of Proteasomal Protein Catabolic Process Transcription Repressor Complex Tumor Necrosis Factor-mediated Signaling Pathway Structural Constituent Of Skin Epidermis RNA Processing TORC1 Signaling Negative Regulation Of TORC1 Signaling Regulation Of Alternative MRNA Splicing, Via Spliceosome Nerve Maturation Response To Odorant Protein Kinase CK2 Complex Regulation Of Chromosome Separation Regulation Of Intracellular Transport
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