KRT18 and TXNDC11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		KRT18	TXNDC11
Description		keratin 18	thioredoxin domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Intermediate Filament Adherens Junction Nuclear Matrix Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding
	Biological Process	Anatomical Structure Morphogenesis Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells	Thyroxine biosynthesis
Drugs
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715) Nonsyndromic cleft lip with cleft palate ( 28232668)	Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 24390342 30423114) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		94 interacting genes: AIRIM BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCHCR1 CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EFHC1 EGFR EP300 ESR1 EXOC8 FRAT1 FXR1 FXR2 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 HSPB1 IKBKG KIFC3 KPNA2 KRT15 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LDOC1 LINC01554 MAPK14 NEFL NME7 ORC5 PDE4B PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE PSTPIP2 RAF1 RCOR3 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SVIL SYCE1 TCHP TEKT4 TNFRSF1B TRADD TSG101 TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A WBP2 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	22 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 NRIP1 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417
Entrez ID		3875	51061
HPRD ID		01020	07125
Ensembl ID		ENSG00000111057	ENSG00000153066
Uniprot IDs		P05783	Q6PKC3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Cytoplasm Organelle Organization Cytoskeleton Organization Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Cytoskeleton Establishment Of Protein Localization Nucleus Developmental Process Supramolecular Fiber Organization BBSome Regulation Of Apoptotic Process Intracellular Protein Localization Protein Domain Specific Binding Regulation Of Programmed Cell Death Cellular Component Assembly Centrosome Regulation Of Protein Metabolic Process Keratinization Establishment Of Localization In Cell Reproductive Process Response To Lipid Enzyme Binding Apoptotic Process Protein Binding Regulation Of Cellular Component Organization Programmed Cell Death Cell Death Cellular Response To Staurosporine Ciliary Basal Body Cellular Localization Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Hippocampus Development Regulation Of Microtubule Nucleation Phosphoserine Residue Binding Focal Adhesion Pyroptotic Inflammatory Response Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of Macromolecule Biosynthetic Process Death-inducing Signaling Complex Desmosome Assembly	Superoxide-generating NAD(P)H Oxidase Activity Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification Thyroid Hormone Metabolic Process Cuticle Development Reactive Oxygen Species Metabolic Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Cytokine-mediated Signaling Pathway Cellular Detoxification Heme Binding Hormone Biosynthetic Process Ovulation Cycle Process Superoxide Metabolic Process Hydrogen Peroxide Biosynthetic Process Scaffold Protein Binding NAD(P)H Oxidase H2O2-forming Activity Erythrocyte Differentiation Ovulation Phenol-containing Compound Metabolic Process Reactive Oxygen Species Biosynthetic Process NADPH Oxidase Complex Superoxide Anion Generation Nuclear Matrix Regulation Of Wound Healing Lipid Storage Response To Purine-containing Compound Acetate CoA-transferase Activity Phenylacetate Catabolic Process NADP Binding Modified Amino Acid Metabolic Process Iodide Peroxidase Activity Ovarian Follicle Rupture Histone H2AS1 Kinase Activity Regulation Of Response To Wounding Protein Kinase Inhibitor Activity Tissue Morphogenesis Catabolic Process Cytosol Cellular Response To Cytokine Stimulus Hormone Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?